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BIO 2 EK

QuestionAnswer
polymorphism poly - many; many alleles = many forms of a phenotype
speciation causes -inbreeding: when separated geographically & mutation happens in one group but not other - random events - disaster - bottleneck: allele freq of pop shift - specialization: tailor behavior to exploit env - adaptation: gen/behav change = advant in env
Hardy Weinburg Equil no evol happens = no change in allele freq of pop only if: 1. mutation equilibrium 2. no emigration or immigration 3. no natural selection 4. random mating (=/= select) 5. large pop
genetic drift one allele maybe forever lost due to death of all members with it
differential reproduction best adapted to environment = most likely to survive to reproductive age and have offspring nat selection is the differential survival and reprod of indivs
viral particle mature virus outside host, or viron
lytic infection virus that causes disease - virulent virus: use cell machinery to make more viral components infection to lysis: latent period
lysogenic infection viral DNA is incorporated in genome of host - host replicates = virus too temperate virus: maybe no symptoms dormant or latent - provirus
enveloped vs noneveloped viruses E: leave cell, body does not detect, binds other cells - host eventually dies N: lyses cell and cause cell death on their release
+ RNA vs - RNA + can be translated into protein just like regular mRNA - RNA has to be transcribed again to get + RNA and then it can be translated
retroviruses some ssRNA viruses are called this: transcribe RNA into dsDNA with reverse transcriptase. hard to eradicate, attack immune syst
subviral particles infectious agents related to virus viroids: naked RNA w/o capside, infect plants prions: naked protein infect animals (cant reprod selves w/o DNA or RNA) - p: people: animals
gram + bacteria plasma membrane - peptidoglycan (cell wall) - envelope stains purple bc lots of ^ cell wall is porous so L molecs can pass
gram - bacteria plasma membrane - peptidoglycan (cell wall) - outer plasma membrane (more permeable than inner) - envelope stains pink bc less p
flagellar propulsion with flagella (made of globular protein flagellin) can move towards food and such. Uses E from proton gradient to move, not ATP
genetic recombination allow bact to trade DNA - conjugation - transformation - transduction
conjugation transfer of plasmid to other bacteria (plasmid =/= need for survival) - must have gene for sex pilus - F plasmid/fertility factor/f factor: codes for sex pilus (bact w/ it +, w/o it -) - R plasmid/R factor: resistance to Ab
plasmid (s circles of extragenomic DNA) if plasmid integrates into chromosome also called an episome
transformation bact incorporate DNA from outside env into genome
transduction transfer of genetic material by virus ex: bacteriophage accidentally grabbed host DNA & injects this into next bact virus that mediates transduction is a vector
Prok vs Euk P: cell walls of peptidoglyc. Flagella from flagellin. E: if have cell walls, of chitin (fungi) or cellulose (plants). Flagella from microtubules
smooth ER think: lipid metabolism & storage, detox
peroxisomes vesicles in cytosol, lipid & protein storage. Don't bud off, incorporate prots & lipids make & break hydrogen peroxide inactivate toxic substances, reg [O2], make/break lipid, metab N bases & carbs
mitoch like proks, have circular DNA replicates indep - ab blocks prok ribosomes but not euk ribosomes? also blocks mitoch ribs - like gram - bact, has inner (ETC) and outer memb
cytoskeleton parts microtubules (biggest) intermediate filaments microfilaments (smallest)
microtubules tubes - for transport within cell & support shape. hollow, of tubulin (globul prot) - end is at MTOC microtub org center grows away from it to make + end ex centrosome (comp of pair centrioles) form flagella & cilia 9+2 dynein: connects microtubs
microfilaments aka actin filaments; reshape cell memb interact w/ myosin = muscle contraction pinching of cytoplasm during cytokinesis (cleavage)
intermediate filaments maint cell shape - structural rigidity bc not as dyanamic as other 2 keratin - hair & skin
lysosomes need low pH to work so when they catch something, its enzymes are activated by pumping protons into interior
amphipathic sounds like fat - has both polar and nonpolar (fat) portion
electrical gradient direction + particle will tend to move
membrane permeability size & charge - small & neutral if polar: hard to cross if big: hard to cross if charged: harder to cross
facilitated diffusion something FACILITATES crossing of molecule but down electrochemical gradient - L or charged molecs
simple or passive diffusion just go from high to low [ ] thru holes - small or nonpolar molecs
active transport ACTIVE = needs E to be active & help molecs move against gradient primary: use ATP (Na/K pump) secondary: use E from gradient of one molec down gradient to move another against gradient - symporter or antiporter
hypertonic cells they are HYPER (more) []d than the outside env in = higher solute, low water water comes in = explodes
hypotonic cells they are HYPO (less) [ ]d than their outside env out = high solute, low water water goes out = shrinks if cell is hypotonic to env
osmotic pressure when [ ] across membranes is different its generated. Pulling pressure generated by [ ] gradient = encourages osmosis - colligative property bc depends on #
hypotonic solution solute [ ] outside cell is lower/water higher than inside cell water moves from high to low = enters cell = explode
hypertonic solution solute [ ] outside cell is higher/water lower than inside cell water moves from high to low = leaves cell = shrinks
cell life cycle stages G1: growing to get ready to divide in S, longest. If not ready enter G0: non growing, some stay forever: neurons, muscles S: DNA replic G2: cell prepS to divide and enter Ms. Organelles keep duplicating prots/RNA ^ interphase Mitosis/Meiosis
intercellular junctions tight junctions: watertight seal from cell to cell, blocks water, ions, proteins - keep from leaking ex bladder, intestines
intercellular junctions desmosomes: join 2 cells @ a single pt, attach directly to cytoskeleton of each cell, in tissue that experiences stress bc of sliding - skin accompany tight j's spot welds
intercellular junctions gap junctions - makes mov of small molecs & ions easier btw cells tunnels
second messengers cAMP, cGMP, calmodulin
Created by: orozcomak
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