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Dimorphic fungi Histoplasma capsulatum; Blastomyces dermatiditis; Sporothrix schenckii; Coccidioides immitis (also C. posadasii); Paracoccidioides brasiliensis; Penicillium marneffei
Yeasts Candida albicans; Candida spp; Torulopsis glabrata; Cryptococcus neoformans; Pneumocystsis carinii
Molds Zygomycetes (nonseptate): Mucor, Rhizopus; Dermatophytic agents: Trichophyton, Malasezzia; Dematiaceous fungi: Alternaria, Cladosporium; Opportunistic fungi: Aspergillus, PenicilliumDimorphic fungi
Fungi mechanismsof dz metabolic toxicity (ingest); hypersensitivity; host colonization with subsequent disease
Opportunistic mycoses Candida spp; Cryptococcus neoformans; Aspergillus spp; Zygomycetes; Fusarium et al; Pneumocystis jiroveci
Infect immunocompetent AND immunocompromised Cryptococcus neoformans
Most common cause of meningitis in HIV & PG Cryptococcus neoformans
Zygomycetes (nonseptate) Mucor, Rhizopus
Dermatophytic agents Trichophyton, Malasezzia
Dematiaceous fungi Alternaria, Cladosporium
Opportunistic fungi Aspergillus, Penicillium
Dermatophytic agents Trichophyton, Malasezzia
nail infxn example of what level of tissue invasion by fungi? Cutaneous
Which dimorphic fungi to suspect in immunocompetent people? Blasto
Superficial mycoses causing hypigmentation M. furfur
Ringworm dermatophytes (2 phytons & microsporum)
More common in tropical M furfur; subcutaneous
Immunocompromised pt Histo, coccidioides, Candida, Aspergillus (direct tissue invasion)
Olive oil; tinea versicolor; spaghetti & meatballs; pseudohyphae M. furfur
Systemic fungal infxn originate usually in the ____ Lung (but can disseminate)
colonizes human airway Aspergillus (in immunocomp pt can cause direct tissue invasion)
conidia bind to human fibrinogen; problems for neutropenic pt Aspergillus
most common opportunistic fungi Candida spp
invades deep tissues of multiple organs Candida spp
can make pseudohyphae M. furfur; candida spp
Encapsulated yeast; CNS; meningitis Cryptococcus neoformans
Example of nonpigmented (hyaline) mold fusarium
Diagnosis by bronchial lavage (OR); silver stain pneumocystis
subcutaneous Sporo; Chromoblastomycosis; Mycetoma
lesions develop along lymphatic sporo
lesions often pathognomonic systemic mycoses
Created by: Abarnard



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