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ch 39Rat Bite Fever

Streptobacillus moniliformis and Spirillum minus

An infectious disease that can be caused by two different bacteria? Rat bite fever
Transmission of Rat Bite Fever contact with infected rodents ingestion contaminated food or water
When Rat Bite Fever is contracted thru contaminated food, water, and most often milk the disease is known as Haverhill fever
What 2 bacteria cause Rat Bite Fever? Streptobacillus moniliformis Spirillum minus
The only bacterial cause of Haverhill fever is? Streptobacillus moniliformis
s/s Haverhill fever fever, chills, joint pain, rash on hands and feet
rare complications of Haverhill fever are? Endocarditis and meningitis
S. moniliformis epidemiology implicates infection via comsumption of? Milk
Mortality rate of untreated Rat Bite Fever is? 10%
In the US most cases are found in what 3 groups? children with pet rats lab workers pet shop employees
General characteristics of S. moniliformis Facultatively anaerobic Nonmotile Highly pleimorphic
General characteristics of S. minus gram negative; helical Strictly aerobic Can't be cultured
S, moniliformis is the normal flora of upper respiratory tract of rats
S. moniliformis is transmitted by rat bite ingestion of contaminated food
Symptoms of infection with S. moniliformis can occur as early as 12 hours after exposure
S. moniliformis causes acute onset of fever, chills, headache, vomiting, joint pain, rash on palms of hands and soles of feet
Fever may last weeks or months
Gram stain of Streptobacillus moniliformis pleimorphic, gram neg, rod "string of pearls"
Requirements for growth blood, ascitic fluid or serum
Cultivation BAP with CO2
Appearance of S. moniliformis in broth "fluff balls" or "bread crumbs"
Appearance of S. moniliformis colonies fried egg
Motility of S. moniliformis nonmotile
S. moniiiformis is biochemically inert, only positive for H2S
Transmission of Spirillum minus rat bite
What is Soduku? Asian RBF caused by Spirillum minus
The symptoms of S. minus infection are similar to S. moniliformis except arthritis is rare
Incubation of S. minus compared to S. moniliformis longer
S. minus morphology spiral, gram neg
Diagnosis S. minus injection lesion material or blood into white mice or guinea pigs
In S. minus what sign is prominent swollen lymph nodes
in S. minus the wound spontaneously heals, then reulcerates
S. moniliformis is found in region? North America
Created by: nawchem