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FAS enzymes

names and functions of enzymes present in E. coli fatty acid synthase complex

QuestionAnswer
Acyl carrier protein (ACP) carries acyl groups in thioester linkage
Acetyl-CoA-ACP transacetylase(AT) transfers acyl group from CoA to Cys residue of KS
beta-Ketoacyl-ACP synthase(KS) condenses acyl and malonyl groups (at least 3 isozymes)
Malonyl-CoA-ACP transferase(MT) transfers malonyl group from CoA to ACP
beta-Ketoacyl-ACP reductase(KR) reduces beta-keto group to beta-hydroxyl group
beta-hydroxyacyl-ACP dehyratase(HD) removes H2O from beta-hydroxyacyl-ACP, creating double bond
Enoyl-ACP reductase(ER) reduces double bond, forming saturated acyl-ACP
Created by: phantomkiwi