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Adipose &chol

Adipose & lipoproteins

What is adipose tissue made up of? Cells (pre-adipocytes, adipocytes and immune cells), connective tissue, nerve tissue and blood vessels
What proteins does adipose tissue release? Adipokines (leptin, adiponectin, resistin, pro-inflammatory cytokines)
What are the main exports from adipocytes? Fatty acids, glycerol and adipokines
ApoB 100 is attached to which lipoproteins? LDL, IDL and VLDL
Why are small dense LDLs bad? LDLs will only bind to their receptor at a certain size to get cleared. The biggest ones get taken up more rapidly. The small ones have a low affinity for the receptor. The longer LDLs are in circulation, the more damage they can do.
Why are small dense HDLs bad? Because they get cleared more quickly and less remain in circulation to help counteract the negative actions of LDL
Apo48e is attached to which lipoprotien? Chylomicrons
What are some of the key benefits of high HDL levels? They reduce the inflammatory response and they stop oxidation of LDL
Created by: KatApple