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Hypertension mgmt
Question | Answer |
---|---|
What are the three main categories of anti-hypertensive drugs? | 1. Diuretics 2. beta-adrenoreceptor antagonists 3. Vasodilators |
How do antihypertensives work? | By inhibiting steps in the RAAS system |
How do diuretics work? | They work against ADH and excrete water and sodium from the kidney. |
How do beta-adrenoreceptor antagonists work? | Resets peripheral resistance --> heart doesn't beat as forcefully |
What are the 4 different categories of vasodilators? | ACE inhibitors, Angiotensin receptor antagonists, calcium channel blockers and alpha1- adrenoreceptor antagonists |
How do ACE inhibitors work? | Prevents the conversion of angiotensin I to angiotensin II. (Angiotensin is a powerful vasoconstrictor) |
How do angiotensin receptor antagonists work? | They block the binding of angiotensin to it's receptor |
How do calcium channel blockers work? | Block the entry of calcium into the cell. (Smooth muscle tone is controlled by cystolic calcium) |
How do alpha1- adrenoreceptor antagonists work? | Block cystolic calcium from entering the cell and selectively block vascualar alpha1 receptors |
What dietary patterns are successful in reducing Hypertension? | DASH, Nordic & Mediterranean |
Which groups of people are more likely to be sensitive to sodium restriction? | People with preexisting hypertension, diabetes or chronic kidney disease, overweight/obese, elderly |