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Hypertension mgmt

What are the three main categories of anti-hypertensive drugs? 1. Diuretics 2. beta-adrenoreceptor antagonists 3. Vasodilators
How do antihypertensives work? By inhibiting steps in the RAAS system
How do diuretics work? They work against ADH and excrete water and sodium from the kidney.
How do beta-adrenoreceptor antagonists work? Resets peripheral resistance --> heart doesn't beat as forcefully
What are the 4 different categories of vasodilators? ACE inhibitors, Angiotensin receptor antagonists, calcium channel blockers and alpha1- adrenoreceptor antagonists
How do ACE inhibitors work? Prevents the conversion of angiotensin I to angiotensin II. (Angiotensin is a powerful vasoconstrictor)
How do angiotensin receptor antagonists work? They block the binding of angiotensin to it's receptor
How do calcium channel blockers work? Block the entry of calcium into the cell. (Smooth muscle tone is controlled by cystolic calcium)
How do alpha1- adrenoreceptor antagonists work? Block cystolic calcium from entering the cell and selectively block vascualar alpha1 receptors
What dietary patterns are successful in reducing Hypertension? DASH, Nordic & Mediterranean
Which groups of people are more likely to be sensitive to sodium restriction? People with preexisting hypertension, diabetes or chronic kidney disease, overweight/obese, elderly
Created by: KatApple