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Diagnostic Img.2 EX2

Tumors & Trauma & Cumulative from EX 1

Solitary lytic or blastic in pt. over 40 suggests? Cancer, consider metastasis and multiple myeloma
Solitary diaphyseal lucency in any pt. suggests? Cancer, consider leukemia and neuroblastoma in kids, and reticuloendothelial cancer in adults
Most common skeletal cancer? lytic metastasis
Bilateral symmetry suggests? normal variant
Pt. > 40 have cancer
Pt. < 40 have benign lesions, exception is teenagers
Diffuse osteopenia is a male may be the only sign of? multiple myeloma
Calcified lesions are usually? benign, except chondrosarcoma
Thick sclerotic rim suggests? benign lesion or fibrous lesions
Mets favors and Myloma spares? Pedicles
Long lesions in long bones are usually? fibrous
Most common skeletal malignancy? metastasis
Metastasis travels via? lymph, blood or body fluids
Metastatic area will have what type of cancer cells? cancer cells from the original lesion. (they are secondary lesions)
Types and percentages of metastatic lesions? 70% are lytic, 20% are blastic, 10% are mixed
Most common blastic mets in men? prostate
Most common Blastic mets in woman? breast
Bacon, lettuce & tomatoe w/ketch up & pickles Breast, lung, thyroid, kidney & prostate
Loves the pedicles of the spine? metastasis
Likes the flat bones? (older people) Metastasis
May be the first sign of malignancy? metastasis
Blow out metastasis generally associated with rapid growth cells
Entire structure will be destroyed? blow out metastasis
Blow out metastasis most common from? lung, kidney, and thyroid
Unusual for mets? go distal to knee or elbow
Mets prefers... flat bones
If mets found distal to knee or elbow think... lung metastasis; also kidneys or thyroid
Mets appear as punched out lytic lesions of what size in flat bones? varying size (ovoid, not good margins)
Multiple myeloma will appear as punch out lytic lesions of what size in flat bones? symmetrical (circular, sharp margins)
Blastic mets appears... opaque, loose (ivory vertebrae)
metastasis commonly look "motheaten"; poorly marginated
multiple myeloma involves? bone marrow
multiple myeloma is a maligant tumor of? plasma cells, arising from a single clone
Multiple myeloma accounts for what percentage of primary malignant tumors of bone? > 40%
Most common malignant primary bone tumor? multiple myeloma
Multiple myeloma may arise as single intraosseous tumor called? plasmacytoma
plasmacytomas appear as soap bubble lesions, not punched out
multiple myeloma more often develops as? multiple painful lesions throughout skeleton
multiple myeloma findings * M spike on serum protein electrophoresis* Diffuse osteopenia in relatively young man* Spinal osteopenia w/compression fx* Multiple lucent lesions in flat & long bone*Proteinuria=Bence Jones
multiple myeloma likes flat bones because? that's where bone marrow is
Reticuloendothelial cancers 1)leukemia 2)lymphoma 3)Multiple myeloma
Osteosarcoma found in teens
malignant tumor of bone in which neoplastic osteoid is produced? osteosarcoma
Most common primary malignant bone tumor of mesenchymal derivation? osteosarcoma
how many types of osteosarcomas? 17
classic type of osteosarcoma? central osteosarcoma--found in central part of bone like the knee, hip or shoulder
uncommon, but kills most of its victims osteosarcoma
deformity is common osteosarcoma
Osteosarcoma is a malignancy of what? bone (osteocyte) so it is a bone forming tumor
Osteosarcoma's periosteal reation? spiculated or sunburst
osteosarcoma may have what associated with it? soft tissue mass
Osteosarcoma's onset? insidious
Osteosarcoma is most common primary malignancy of bone because? it is of the bone cells
multiple myeloma is the most common skeletal malignancy because? it occurs in the bone marrow
arises in adolescents and affects males slightly more that females osteosarcoma
affected sites of osteosarcoma 1)knee(distal femur or proximal tibia) in 50% of pt. 2)proximal humerus 3)proximal femur 4)pelvis
osteosarcoma mostly occur in what part of the bone? metaphysic
may see what periosteal reaction with osteosarcoma? Codman's triangle
what is codman's triangle? left over periosteal rxn when tumor has moved outside the bone
chondrosarcoma lytic distruction that doesn't cross the SI joint
what type of tumor is chondrosarcoma? malignant cartilaginous tumor of the bone
Chondrosarcoma compared with osteosarcoma less common and less aggressive
Staging of chondrosarcoma most often presents as a low grade-intracompartmental lesion
slow to metastasize and may grow to immense proportions chondrosarcoma
typically lytic and with calcifications chondrosarcoma
locations of chondrosarcoma 1)pelvis(most common) 2)femur 3)shoulder girdle
chondrosarcoma of the femur is a secondary chondrosarcoma because... it arises from pre-existing osteochondroma because it begins to hurt and forms a bursa. Cartilaginous cap undergoes malignant degeneration
Created by: 827753675
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