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Neuro-congenital Dis

Neuromuscular Congenital Diseases / Treatment

QuestionAnswer
Cerebral Palsy: Lesion in Motor Cortex Spacticity with flexor/extensor imbalance
Cerebral Palsy: Lesion in Basil Ganglia Fluctuation in muscle tone, dyskinesia (involuntary, non repetitive movement), dystonia, lack of co-contraction with writhing.
Cerebral Palsy: Lesion in Cerebellum ataxic movements, less stable - more primitive
Affected limbs determine classification: Monoplegic, Hemiplegic, Paraplegic, Quadraplegic, and Diplegic
Parkinson's Disease Tremor, rigidity, resistance to prom, akinesia, festinating gate (shuffled) micrographia, and/or face mask (inability to move facial muscles)
Parkinson's Progression according to Hoehn and Yahr 1. Unintentional tremor, rigidity, akinesia independent with ADLs. 2. Bilateral tremor, rigidity, akinesia, indpendent with ADLs. 3. Worsening symptoms - beginning of ADL impairment. 4. Mild-Mod A with ADLs - unable to live alone. 5. W/c - max A with ADLs
Spina Bifida Occulta external manifestations (patch of hair, open birthmark)
Spina Bifida Meningocele protrusion of CSF into sac
Spina Bifida Myelomeningocele protrusion of CSF and CORD into sac (sensory and motor deficits)
Muscular Dystrophies/Atrophies: Duchenne's Enlargment of calves/forearms (adipose tissue) Gower's sign (hands crawl up thighs to stand)-weakness of proximal joints.
Muscular Dystrophies/Atrophies: Arthrogryposis multiplex congenita Loss of anterior horn cells-joint contracture. Position of UE at rest: internal rotation, extension of elbow, and flexion of wrist.
Muscular Dystrophies/Atrophies: Limb Girdle proximal muscles of the shoulders and pelvic girdle
Muscular Dystrophies/Atrophies: Fascioscapulohumeral Face, Upper arm, and Scapular Involvement
Muscular Dystrophies/Atrophies: Spinal Muscular Atrophy Werdnig-Hoffman...life expectancy of 2 years.
Muscular Dystrophies/Atrophies: Congenital Myasthenia Gravis disorder of transmission in the neuromuscular junction.
Progressive Supranuclear Palsy Loss of voluntary eye movement, bradykinesia, rigidity, pseudobulbar palsy (loss of control of facial muscles), dementia.
Created by: hesselrach