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Question | Answer |
---|---|
What Cells to Rickettsia target | reticuloendothelial cells Vascular endothelial cells Erythrocytes |
What disease does Ricketssia prowazekii cause | Typhus |
What disease does Ricketssia rikettsii cause | Rocky mountain spotted fever |
Anaplasma marginale targets what cell | RBC |
What are the symptoms of Anaplasma marginale | sever anemia, depression, inapppetance, fever, dehydration, death |
how do you diagnosis Anaplasma marginale | Geimsa stain Acridine Orange - parasite lives on edge of RBC |
What disease does Neorickettsia helminthoeca cause | Salmon poisoning |
What disease does Neorickettia risticci cause | Potomac Horse fever |
What form of Chlamydia is infective | the Elementary bodies |
What disease does Chlamydia psittaci cause | Psittaccosis |
What species does Chlamydia psittaci infect | green Amazon parrots & Shell parakeets |
What are symptoms of Chlamydia psittaci | anorexia, green urates, mucopurulant nasal discharge, eyes pasted shut, emaciated & dehydrated |
What is the treatment for Chlamydia psittaci | Chlorotetracyline |
What disease does Bortonella henselae cause | Cat Scratch fever |
What disease does Moraxella bovis cause | Infectious bovine keratoconjunctivitis |
What causes the onset of the disease with Moraxella bovis | solar UV radiation |
What predisposes a cow with having disease correlated with Moraxella bovis | cattle w/ no pigment around eyelids cattle w/ prominent placed eyes |
What are some symptoms of infectious bovine keratoconjunctivitis | Early stage: excessive tear production Later stage: eye becomes cloudy, eye ulcer, ulcer may rupture, low weight gain |
What is the correlations with M. bovis and calf/dam | if M. bovis is isolated from the calf than it is causing disease If M. bovis is isolated from dam, than it does not mean it is causing disease |
How do you treat M. bovis | good management practices provide shade dust bags/ insectidies Oxytetracycline |
How is Pseduomonas aeruginosa identified | it has a green appearance with a "grape" fruity odor when grown at 42c |
What diseases does Pseduomonas aeruginosa cause | Dairy cows: mastitis Dogs: Suppurative otitis externa Sheep: Green wool Minks/Chinchilla: hemorrhagic pneumonia |
What makes Pseduomonas aeruginosa hard to treat? | Biofilms |
How are biofilms adaptive to bacteria | they are antiphagocytic protect them from antimicrobials they mutate at higher frequency --> more genetic diversity--> increase population fitness |
How do biofilms effect Animal farming | inaccurate antibacterial testing microbes in biofilms are more resistant inaccurate water quality monitoring thick biofilms can block water supply biofilms act as seeding grounds |
Why is Pseduomonas aeruginosa resistant to antibiotics | it has: multidrug efflux pumps multiple plasmid & chromosomally-encoded antibiotic resistant genes low permeability of the bacterial cellular envelope |
Burkolderia pseudomallei causes what disease | Melioidosis: associated w/ suppurative or caseous lesions |
How do you diagnosis Burkolderia pseudomallei | grow on Ashdown's media or PCR |
Burkholderia mallei causes what disease | Glanders disease |
What are the 3 forms of the disease caused by Burkholderia mallei | Nasal form Pulmonary form Cutaneous form: "Farcy" causes lymphadenitis & lymphagitis |
What is the unifying characteristic of the CMN group? | mycolic acid |
Mycolic acid confers what? | hydrophobicity resistance to acid & alkali resistance to humoral defense mechanisms resistance to common antibacterial treatments |
Mycobacterium characterisitics | acid fast phenotype grow on middlebrooks' media and Lowenstein-Jensen media Can be enriched w/ a 1:1000 bleach & 2%NaOH solution |
How do Mycobacterium tuberculosis granulomas form | The bacteria resists destruction inside a macrophage. More macrophages are attracted to the area and the bacteria lysis the mac and invades other cells, greating a granuloma where dead/inactivated cells are in the center and active cells are surrounding |
What disease does Mycobacterium bovis cause | Bovine tuberculosis |
Mycobacterium avium causes | Mycobacterium avium paratuberculosis complex (MAP) Disease: Johne's Disease |
What are the clinical signs of Mycobacterium avium | illeum & colon involved Corrugated and thickened mucous membranes |
Corynebacterium are easily identified by: | old cells store inorganic phosphate and have metachromatic granules Cell morphology "palisades" (picket fence), Chinese letters |
Corynebacterium pseudotuberculosis causes: | caseous lymphadenitis |
Cornebacterium renale cause | Posthitis (pizzle rot) Pyelonephritis UTI |
Cornebacterium renale pathogenensis is: | urease is produced --> ammonia is produced which irritates prepuce allowing bacteria to invade |
Rhodococcus equi causes clinical disease in foals how old | 4-12 weeks of age |
Rhodococcus equi can cause a secondary disease called: | enteritis a sequally to foal pneumonia |
Rhodococcus equi causes: | foal pneumonia |
Listeria causes 4 types of listeriosis what are they: | Intestinal Visceral :septicemic Abortive Neural: "Circling Disease" - menigoencephalitis |
What are some clinical signs for Neural Listeriosis | circling, seizures, facial nerve paralsis, ear drop, salivation, lock jaw, impaired swelling, death |
What are the stages of infection for Listeria | Internalization: induce phagocytosis Escape from phagolysosme Nucleation of actin filiments: moves to cell membrane Cell-to-cell spread: invades other cells through pseudopod-like projections Membrane vacuoles: lyse cell membrane releasing bacteria |
Erysipelothrix rhusiopathiae causes what disease | Dimond skin disease in pigs |
Aerotolerant anaerobes means what | can grow with or without oxygen |
obligate anaerobe means what | lack superoxide dismutase, catalase, and peroxidase cant grow in presence of oxygen |
When culturing anaerobes what needs to be incorporated in the media? | reducing agents |
Healthy tissue Eh value is what? | ~+150mvolts |
Anaerobosis takes place when tissue Eh decreases. What can cause this to occur. | loss of vascular supply Trauma, foreign bodies, pressure from casts acid production by aerobes or facultative anaerobes tissue necrosis from trauma, infection or surgical manipulation |
Clostridum chauvoei causes what disease | Black leg disease |
Clostridum septicum causes: | Malignant edema |
Clostridum hemolyticum causes: | Red water disease -hemoglobinuria |
Clostridum novyi causes: | Gas gangrene Black disease |
Clostridum piliforme causes: | Tyzzer's disease Necrotizing hepatitis Hemorrhagic enteritis |
Clostridum perfringens causes | Yellow lamb disease- Purple Gut Lamb dysentery Hemorrhagic & necrotic enteritis Pulpy Kidney Disease "overeating disease" |
Clostridium tetani acts by: | blocking the release of GABA/glycine leading to dangerous over activity in the muscles |
Clostridium botulinium acts by | binding to receptors at neuromecular junctions--> muscles fail to contract --> flaccid paralysis |
Fusobacterium necrophorum causes | Necrobacillosis: necrosis, abscess formation, and putrid odor Calf diptheria Foot rot |
Bacteroides nodosus causes | contagious foot rot as secondary invader w/ F. necrophorum |
Bacteroides melaniogenicus causes | Foot rot w/ F. necrophorum |
Bacillus cereus causes | gangrnous mastitis Food posioning: Emetic & Diarrheal form |
Bacillus anthracis has 3 forms | Peracute, acute, chronic |
what are the virulance factsors of Bacillus anthracis | Edema factor Protective Antigen Lethal Factor |
Actinomyces bovis causes | Lumpy Jaw disease |
Aranobacterium pyogenes causes | Heal abscess in sheep w/ F. necrophorum |
Dermatophilus congolensis causes | Dermatophilosis |
Haenophilus paragallinarum | Fowl coryza |
Actinobacillus pleuropneumonia | Sudden death of swine |
Actinobacillus lignieresii | Wooden tongue |
Campylobacter fetus venerealis | tissue tropism in repro tract |
Clostridium novyi | Black Disease & gas gangrene |
Francisella tularensis | Tularemia |
Clostridium piliforme | Tyzzer's Disease |
Pseudomonas aeruginosa | Necrotic Pneumonia |
Burkholderia mallei | Glander's |
Clostridium tetani/botulinum | Tetanus/ Botulism |
Campylobacter fetus fetus | Tissue tropism in intestinal tract |
Clostridium speticum | Malignant edema |
Camplyobacter jejuni | Food bourne enteritis |
Haemophilus somni | Thromboembolic Menigoencephalitis |
Actinobacillus equuli | Purulent joint and kidney abscess |
Lawsonia interacellularis | Porcine Proliferative enteritis |