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BacT
| Question | Answer |
|---|---|
| What Cells to Rickettsia target | reticuloendothelial cells Vascular endothelial cells Erythrocytes |
| What disease does Ricketssia prowazekii cause | Typhus |
| What disease does Ricketssia rikettsii cause | Rocky mountain spotted fever |
| Anaplasma marginale targets what cell | RBC |
| What are the symptoms of Anaplasma marginale | sever anemia, depression, inapppetance, fever, dehydration, death |
| how do you diagnosis Anaplasma marginale | Geimsa stain Acridine Orange - parasite lives on edge of RBC |
| What disease does Neorickettsia helminthoeca cause | Salmon poisoning |
| What disease does Neorickettia risticci cause | Potomac Horse fever |
| What form of Chlamydia is infective | the Elementary bodies |
| What disease does Chlamydia psittaci cause | Psittaccosis |
| What species does Chlamydia psittaci infect | green Amazon parrots & Shell parakeets |
| What are symptoms of Chlamydia psittaci | anorexia, green urates, mucopurulant nasal discharge, eyes pasted shut, emaciated & dehydrated |
| What is the treatment for Chlamydia psittaci | Chlorotetracyline |
| What disease does Bortonella henselae cause | Cat Scratch fever |
| What disease does Moraxella bovis cause | Infectious bovine keratoconjunctivitis |
| What causes the onset of the disease with Moraxella bovis | solar UV radiation |
| What predisposes a cow with having disease correlated with Moraxella bovis | cattle w/ no pigment around eyelids cattle w/ prominent placed eyes |
| What are some symptoms of infectious bovine keratoconjunctivitis | Early stage: excessive tear production Later stage: eye becomes cloudy, eye ulcer, ulcer may rupture, low weight gain |
| What is the correlations with M. bovis and calf/dam | if M. bovis is isolated from the calf than it is causing disease If M. bovis is isolated from dam, than it does not mean it is causing disease |
| How do you treat M. bovis | good management practices provide shade dust bags/ insectidies Oxytetracycline |
| How is Pseduomonas aeruginosa identified | it has a green appearance with a "grape" fruity odor when grown at 42c |
| What diseases does Pseduomonas aeruginosa cause | Dairy cows: mastitis Dogs: Suppurative otitis externa Sheep: Green wool Minks/Chinchilla: hemorrhagic pneumonia |
| What makes Pseduomonas aeruginosa hard to treat? | Biofilms |
| How are biofilms adaptive to bacteria | they are antiphagocytic protect them from antimicrobials they mutate at higher frequency --> more genetic diversity--> increase population fitness |
| How do biofilms effect Animal farming | inaccurate antibacterial testing microbes in biofilms are more resistant inaccurate water quality monitoring thick biofilms can block water supply biofilms act as seeding grounds |
| Why is Pseduomonas aeruginosa resistant to antibiotics | it has: multidrug efflux pumps multiple plasmid & chromosomally-encoded antibiotic resistant genes low permeability of the bacterial cellular envelope |
| Burkolderia pseudomallei causes what disease | Melioidosis: associated w/ suppurative or caseous lesions |
| How do you diagnosis Burkolderia pseudomallei | grow on Ashdown's media or PCR |
| Burkholderia mallei causes what disease | Glanders disease |
| What are the 3 forms of the disease caused by Burkholderia mallei | Nasal form Pulmonary form Cutaneous form: "Farcy" causes lymphadenitis & lymphagitis |
| What is the unifying characteristic of the CMN group? | mycolic acid |
| Mycolic acid confers what? | hydrophobicity resistance to acid & alkali resistance to humoral defense mechanisms resistance to common antibacterial treatments |
| Mycobacterium characterisitics | acid fast phenotype grow on middlebrooks' media and Lowenstein-Jensen media Can be enriched w/ a 1:1000 bleach & 2%NaOH solution |
| How do Mycobacterium tuberculosis granulomas form | The bacteria resists destruction inside a macrophage. More macrophages are attracted to the area and the bacteria lysis the mac and invades other cells, greating a granuloma where dead/inactivated cells are in the center and active cells are surrounding |
| What disease does Mycobacterium bovis cause | Bovine tuberculosis |
| Mycobacterium avium causes | Mycobacterium avium paratuberculosis complex (MAP) Disease: Johne's Disease |
| What are the clinical signs of Mycobacterium avium | illeum & colon involved Corrugated and thickened mucous membranes |
| Corynebacterium are easily identified by: | old cells store inorganic phosphate and have metachromatic granules Cell morphology "palisades" (picket fence), Chinese letters |
| Corynebacterium pseudotuberculosis causes: | caseous lymphadenitis |
| Cornebacterium renale cause | Posthitis (pizzle rot) Pyelonephritis UTI |
| Cornebacterium renale pathogenensis is: | urease is produced --> ammonia is produced which irritates prepuce allowing bacteria to invade |
| Rhodococcus equi causes clinical disease in foals how old | 4-12 weeks of age |
| Rhodococcus equi can cause a secondary disease called: | enteritis a sequally to foal pneumonia |
| Rhodococcus equi causes: | foal pneumonia |
| Listeria causes 4 types of listeriosis what are they: | Intestinal Visceral :septicemic Abortive Neural: "Circling Disease" - menigoencephalitis |
| What are some clinical signs for Neural Listeriosis | circling, seizures, facial nerve paralsis, ear drop, salivation, lock jaw, impaired swelling, death |
| What are the stages of infection for Listeria | Internalization: induce phagocytosis Escape from phagolysosme Nucleation of actin filiments: moves to cell membrane Cell-to-cell spread: invades other cells through pseudopod-like projections Membrane vacuoles: lyse cell membrane releasing bacteria |
| Erysipelothrix rhusiopathiae causes what disease | Dimond skin disease in pigs |
| Aerotolerant anaerobes means what | can grow with or without oxygen |
| obligate anaerobe means what | lack superoxide dismutase, catalase, and peroxidase cant grow in presence of oxygen |
| When culturing anaerobes what needs to be incorporated in the media? | reducing agents |
| Healthy tissue Eh value is what? | ~+150mvolts |
| Anaerobosis takes place when tissue Eh decreases. What can cause this to occur. | loss of vascular supply Trauma, foreign bodies, pressure from casts acid production by aerobes or facultative anaerobes tissue necrosis from trauma, infection or surgical manipulation |
| Clostridum chauvoei causes what disease | Black leg disease |
| Clostridum septicum causes: | Malignant edema |
| Clostridum hemolyticum causes: | Red water disease -hemoglobinuria |
| Clostridum novyi causes: | Gas gangrene Black disease |
| Clostridum piliforme causes: | Tyzzer's disease Necrotizing hepatitis Hemorrhagic enteritis |
| Clostridum perfringens causes | Yellow lamb disease- Purple Gut Lamb dysentery Hemorrhagic & necrotic enteritis Pulpy Kidney Disease "overeating disease" |
| Clostridium tetani acts by: | blocking the release of GABA/glycine leading to dangerous over activity in the muscles |
| Clostridium botulinium acts by | binding to receptors at neuromecular junctions--> muscles fail to contract --> flaccid paralysis |
| Fusobacterium necrophorum causes | Necrobacillosis: necrosis, abscess formation, and putrid odor Calf diptheria Foot rot |
| Bacteroides nodosus causes | contagious foot rot as secondary invader w/ F. necrophorum |
| Bacteroides melaniogenicus causes | Foot rot w/ F. necrophorum |
| Bacillus cereus causes | gangrnous mastitis Food posioning: Emetic & Diarrheal form |
| Bacillus anthracis has 3 forms | Peracute, acute, chronic |
| what are the virulance factsors of Bacillus anthracis | Edema factor Protective Antigen Lethal Factor |
| Actinomyces bovis causes | Lumpy Jaw disease |
| Aranobacterium pyogenes causes | Heal abscess in sheep w/ F. necrophorum |
| Dermatophilus congolensis causes | Dermatophilosis |
| Haenophilus paragallinarum | Fowl coryza |
| Actinobacillus pleuropneumonia | Sudden death of swine |
| Actinobacillus lignieresii | Wooden tongue |
| Campylobacter fetus venerealis | tissue tropism in repro tract |
| Clostridium novyi | Black Disease & gas gangrene |
| Francisella tularensis | Tularemia |
| Clostridium piliforme | Tyzzer's Disease |
| Pseudomonas aeruginosa | Necrotic Pneumonia |
| Burkholderia mallei | Glander's |
| Clostridium tetani/botulinum | Tetanus/ Botulism |
| Campylobacter fetus fetus | Tissue tropism in intestinal tract |
| Clostridium speticum | Malignant edema |
| Camplyobacter jejuni | Food bourne enteritis |
| Haemophilus somni | Thromboembolic Menigoencephalitis |
| Actinobacillus equuli | Purulent joint and kidney abscess |
| Lawsonia interacellularis | Porcine Proliferative enteritis |