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Receptor Biology
WVSOM: Subject 5 -- Receptor Biology
| Question | Answer |
|---|---|
| Receptor | a cellular factor that recognizes and binds a specific ligand to induce a response |
| Ligand | a molecule bound by another molecule such as a receptor |
| Intercellular Signaling Molecule | nutrient ligand secreted by one cell to induce a response in another cell |
| Hormone | intercellular signaling molecule that controls metabolism or physiology |
| Growth factor | intercellular signaling molecule that controls cell cycle progression, cellular differentiation, or morphogenesis during development |
| Cytokine | growth factor involved with hematopoiesis |
| Isoreceptors | different receptors bound and activated by the same ligand, often inducing distinct responses in different cells |
| Paracrine | for an intercellular signaling molecule to diffuse over a short distance, usually through interstitial spaces, to induce a response |
| Endocrine | for an intercellular signaling molecule to diffuse through the blood |
| Hydrophobic Ligands | Steroids (cholesterol derivatives) Fatty acid derivatives (prostoglandins, retinoic acid) |
| Hydrophilic Ligands | Amino acid derivatives (catecholamines-tyrosine, histamine-histidine, serotonin-tryptophan) Peptides and proteins (insulin, glucagon, FSH, TGFβ, etc.) Nucleotides (cAMP) No carbohydrates - this is the only major class of biochemicals not used as recept |
| Transport proteins | action potential initiation & propagation |
| Serine/threonine Kinases | Tissue Differentiation Tissue Patterning Immunosuppression Cell Cycle progression |
| Seven Receptor Transmembrane | blood glucose levels metabolism menstrual cycle inflamation glycogenolysis |
| Tyrosine Kinases | blood glucose levels metabolism cell proliferation cell cycle progression differentiation apoptosis. glycogen synthesis |
| TGF-b | Tissue Differentiation Tissue Patterning Immunosuppression Cell Cycle progression |
| Ras | TYROSINE KINASES metabolism glycogen synthesis blood glucose levels cell cycle progression apoptosis. differentiation |
| Phosphoinositide | TYROSINE KINASE cell proliferation |
| cAMP | SEVEN TRANSMEMBRANE RECEPTOR blood glucose levels metabolism glycogenolysis menstrual cycle inflamation |
| synaptic ligand-gated ion channels | TRANSPORT PROTEINS action propagation initiation & potential |
Created by:
tjamrose
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