Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


Chapter 30

What are immunocompromised hosts? These are people with one or more defects in their body's defense mechanisms against microbial invaders.
What are the two groups of immunocompromised hosts? 1. defects in the innate defense mechanimsms 2. deficiencies in the adaptive immune response
Describe primary immunodeficiency? These are inherited or occurs by exposure in utero to environmental factors or by other unknown mechanisms.
Give examples of primary immunodeficiency in innate and adaptive immune system? Innate: complement and phagocyte deficiency Adaptive: T and B cell defects and severe combined immunodeficiency.
Describe secondary immunodeficiency? This is due to an underlying disease state or occurs as a result of treatment for a disease.
Give examples of secondary immunodeficiency in innate and adaptive immune system? Innate: burns, trauma, major surgery, catherization, foreign bodies and obstruction adaptive: malnutrition, infectious diseases, neoplasia, irradiation and chemotherapy
Congenital defects in phagocytic cells confer susceptibility for infection. Name a infection/disease? Chronic granulomatous disease
What is chronic granulomatous disease? An inherited failure to synthesize cytochrome b-245 causes a failure to produce ROS intermediates during phagocytosis. The neutropils cannot kill the invading pathogens
Give examples of how treatment can lead to immunosupression? 1. Cytotoxic agents cause leukopenia, or deranged T and B-cell function. 2. Corticosteroids reducse number of lymphocytes, monocytes and eosinophils 3. Radiotherapy adversely affects the proliferation of lymphoid cells
Why are burn injuries bad? It causes direct damage to the mechanical barries of the body and abnormalities in neutrophil antibacterial function and immune system. Hereby provides a higly nutritious surface for organisms to colonize.
What are the most important pathogens in burn wounds? They are mostly aerobic. Examples: pseudomonas aeruginosa, staphylococcus aureus and streptococcus pyogenes
What bacterial species is the most important cause of surgical wound infection and how is it acquired? Staphylococcus Aureus, acquired during surgery or post operationand may originate from the patient or another patient/staff member.
How can urethral catheters cause damage? The disrupt the normal host defences of the urinary tract and allow organisms easy access to the bladder. Organisms are mostly gram - from patients own feces or from periurethral flora.
How can intravenous and peritoneal dialysis catheters cause damage? They breach the integrity of the skin barrier and allow organisms from the skin flora of the patient or hands from the caretaker easy access to deeper sites.
What bacterial species is the most comman cause of infection from intravenous and peritoneal dialysis catheters? Staphylococci are the most common cause of infection, particularly Staphylococcus Epidermidis.
What bacterial species is an important cause of infection of cardiac pacemakers, grafts and CSF shunts Staphylococcus Epidermidis
Created by: Beantha