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une ch31

gluconeogenesis and maintenance of blood glucose levels

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gluconeogenesis f/s/p Functions: To synthesize glucose from amino acids, lactate & glycerol in order to maintain blood glucose levels. Substrates: Amino acids, lactate, glycerol, ATP, GTP, NADH Product: Blood glucose, ADP, GDP, NAD+
gluconeogenesis control enzymes and regulation Control Enzymes: Fructose 1,6 bisphosphatase Regulation: PEP carboxykinase (induced primarily by cortisol, but also by all the other counterregulatory hormones)
gluconeogenesis compartments and tissues of interest Compartment(s): Pyruvate to Oxaloacetate takes place inside the mitochondria, remainder in cytosol. Glucose 6-phosphatase is in the ER Tissues of interest: Liver mainly. In extreme starvation, the kidney cortex may produce glucose mostly for itself
Created by: carolanimal
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