atherosclerosis Word Scramble
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Question | Answer |
define atherosclerosis | it is a disease where plaque forms in your arteries |
charactersitics | irregular lipid deposits in intima of large/medium arteries - core made out of cholesterol ester - surrounding area - fibrosis and calcification |
consequences of atherosclerosis | haemmorage into plaque, narrowing lumen of artery - low blood flow - thrombosis |
risk factors | advanced agemalesmokingdiabetes mellitushypertension |
risk factors on biochemical level | apo b100,a1,eLCAT;ACATlipoprotein lipase |
clinical implications | myocardial infarctionsenile dementiagangrenesstroke |
treatment | correct lifestyle, proper diet, drugs which INC HDL and DEC VLDL AND LDL eg. statin - inhibits hmg coa reductase + niacin - decrease vldl formation |
T/F -endothelial damage causes the endothelial cells to adhere to LDL | TRUE |
T/F- ENDOTHELIAL CELLS + LDL = MACROPHAGES | TRUE |
t/f macrophages then consume lipoproteins then form CYTOKINES | FALSE |
T/F - macrophages consume lipoproteins and then form foam cells | TRUE |
what do foam cells secrete...? | CYTOKINES - for attraction of other macrophagesGROWTH FACTORS - proliferation of smooth muscle cells and fibroblasts |
smooth muscle cells then produce ___________and take up __________ to become foam cells | collagen lipids |
Created by:
ahmeda101
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