Adrenal Gland Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Question | Answer |
What are the 3 layers of the adrenal cortex? | zona glomerulosa, zona fasciculata, zona reticularis |
Zona glomerulosa is related to what hormone? | Mineralocorticoids (aldosterone) |
Zona fasciculata is related to what hormone? | Cortisol (glucocorticoid) |
Zone reticularis is related to what hormone? | Androgens |
Where are the aromatic amines located? | adrenal medulla |
Cortisol is highest at what time of day? | 8-10am |
Synthesis and release of corticosteroids is stimulated by ________ | ACTH |
_______ plasma cortisol is bound to CBG | 90% |
Adrenal tumor lab values | decreased ACTH, decreased CRF, increased cortisol |
Adrenal nodular hyperplasia lab values | Massive amounts of cortisol produced |
Pituitary Cushings syndrome | increased ACTH, increased cortisol, decreased CRF |
Aldosterone is synthesized in the ________________ | zone glomerulosa |
Aldosterone is controlled by the __________ system | renin-angiotensin system |
Primary Conn's disease (hyperaldosteronism) is due to what? | overproduction of adrenal cortex (inc aldosterone, inc Na retention, inc hypertension) |
Secondary Conn's disease is caused by | CHF, nephrotic syndrome, increased renin production, cirrhosis |
In the zone reticularis, hormone synthesis is under the control of ____________ | ACTH |
common defect in the zona reticularis is __________________ | androgenital syndrome (21-hydroxylase deficiency) |
Congenital adrenal hyperplasia is due to __________ | an inherited defect in the genes of 1 or several steroids. |
What is the most common deficiency in congenital adrenal hyperplasia? | 21-hydroxylase followed by 11B-hydroxylase |
Lab results for congenital adrenal hyperplasia? | Decreased cortisol and aldosterone, increased ACTH and androgens |
Diagnosis for congenital adrenal hyperplasia? | Increased plasma 17-hydroxyprogesterone |
Testosterone is metabolized into what? (2) | Dihydrotestosterone and androtenedione |
What are the 17-ketosteroids? | metabolites of androgens secreted by both the testes and the adrenal gland |
What method is best to measure 17-KS? | Zimmerman reaction at 520nm-------purple compound |
The adrenal medulla contains ________________ | catecholamines |
2 major catecholemines are : | epinephrine and norepinephrine which are synthesized from phenylalanine |
Catecholamines are ____________ biologically active | 100%------------half life of 1min |
Catecholamines are rapidly metabolized by ____________ | catechol-O methyltransferase and monoamine oxidase |
What is the primary metabolite of epinephrine and norepinephrine? | VMA |
Catecholamines are metabolized to ___________ and ____________ | metanephrine and VMA |
What is pheochromacytoma? | Tumor of the chromatin cells of the adrenal medulla due to increased epinephrine and norepinephrine |
How to diagnose pheocytochroma? | Elevated plasma catecholamines and increased urinary VMA and metnaephrines |
Created by:
aenewsom
Popular Laboratory Science sets