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Physiology

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show Inspiration; expiration  
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show Atmospheric pressure  
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____ ____ is the pressure exerted by the air (gases) surrounding the body?   show
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show 760 mmHg = 1 atm  
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show Indicates that the pressure in that area is lower than the atmospheric pressure (Patm)  
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What is positive respiratory pressure?   show
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show Indicates that the pressure in that area is equal to the atmospheric pressure (Patm)  
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What is intrapulmonary pressure?   show
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show Intrapulmonary pressure (Ppul); atmospheric  
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show The pressure in the pleural cavity  
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Intrapleural pressure (Pip) fluctuates with breathing phases, but is always about ___mmHg, less than ____ pressure?   show
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show True  
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show Pneumothorax, pleural effusion  
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Both pneumothorax and pleural effusion put pressure on the lung, causing it to ____?   show
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Because of the ____, lungs always assume the smallest size possible?   show
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show Negative  
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What is transpulmonary pressure?   show
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The ____ pressure keeps the air spaces of the lungs open or keeps the lungs from collapsing?   show
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What is atelectasis?   show
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show Pulmonary  
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show  
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show Boyle  
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The (larger / smaller) the volume the lesser the pressure?   show
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This is the ____ step of inspiration: Inspiratory muscles contract (diaphragm descends; rib cage rises)?   show
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show Second  
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This is the ____ step of inspiration: Lungs stretched; intrapulmonary volume increases?   show
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This is the ____ step of inspiration: Intrapulmonary pressure drops (to -1mmHg)?   show
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This is the ____ step of inspiration: Air (gases) flows into lungs down its pressure gradient until intrapulmonary pressure is 0 (equal to atmospheric pressure)?   show
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show First  
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show Second  
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show Third  
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show Fourth  
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show Fifth  
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What are the three physical factors that influence ventilation?   show
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show Friction; drag  
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Info: Airway resistance - The gas flowing into and out of the alveoli is directly proportional to the pressure gradient between the atmospheric pressure and the alveoli.   show
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show Diameter  
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Normally resistance is (significant / insignificant)?   show
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What are two illness that increase airway resistance?   show
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show Surface tension  
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show Reduce; smallest  
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____ is a detergent-like complex, reduces surface tension and helps keep the alveoli from collapsing?   show
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When too (much/little) surfactant is present, surface tension forces can collapes alveoli. Once this happens, the alveoli must be completely reinflated during each inspiration, an effort that uses tremendous amounts of energy.   show
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Too little surfactant is a problem faced by newborns with ____ ____ ____ ____?   show
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show Lung compliance  
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show Lung compliance  
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What are two factors that determine lung compliance?   show
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show High  
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Fibrosis (scarring) of lungs (increases/reduces) the distensibility of the lungs?   show
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show True  
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show Reduced  
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show False - They do effect compliance  
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What is tidal volume - (TV)?   show
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What is the tidal volume (TV) amount?   show
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What is inspiratory reserve volume (IRV)?   show
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show 3000ml  
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show Air that can be expired from the lungs after a tidal expriation  
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What is the expriratory reserve volume (ERV) amount?   show
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What is residual volume (RV)?   show
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show 1200ml  
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What is inspiratory capacity (IC)?   show
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show Inspiratory capacity (IC)  
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What is functional residual capacity (FRC)?   show
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What is the following formula: ___ = RV +ERV   show
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____ capacity - The total amount of exchangable air?   show
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show 4800 ml  
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show Vital capacity (VC)  
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show Total lung capacity (TLC)  
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show 6000 ml  
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What is the following formula: ___ = VC + RV   show
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show Anatomical dead space (nasal cavity --- terminal bronchioles)  
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show 150 ml  
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Out of ___ ml of TV only ___ ml are involved in alveolar ventilation?   show
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show Alveolar dead space  
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show Total dead space  
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____ - An instrument consisting of a hollow bell inverted over water?   show
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What does a spirometer evaluate?   show
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A spirometer can distinguish between what two disorders?   show
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show Minute ventilation - 500ml x 12 = 6L/min  
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____ ____ capacity - Gas forcibly & rapidly expelled after taking a deep breath?   show
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____ ____ volume - The amount of gas expelled during 1 sec?   show
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A healthy person can expel ___% of FVC in 1 sec?   show
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____ ____ rate - Is a better index of effective ventilation than minute ventilation (takes into account dead space)?   show
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show Alveolar ventilation rate - AVR  
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show Increasing; increases  
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In what condition is FEV decreased?   show
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____ law of partial pressure - The total pressure excerted by a mixture of gases is the sum of the pressures exerted independently by each gas in the mixture?   show
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show Partial pressure  
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show CO2 - 20 times more soluble than O2  
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show Atmospheric is mostly O2 and nitrogen; Alveoli contains more CO2 and water vapor and less O2  
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show Ventilation  
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show Perfusion  
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(T/F) - Ventilation and perfusion must be matched for efficient gas exchange?   show
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show Hemoglobin  
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One molecule of hemoglobin can bind ___ molecules of oxygen?   show
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show Saturated  
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show Saturation  
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The hemoglobin-oxygen combination is called ____ and is written as ____?   show
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Hemoglobin that has released oxygen is called ____ ____ or ____ and is written as ____?   show
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show HHb + O2 (lungs-tissues) HbO2 + H+  
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show PO2: 100 mmHg PCO2: 40 mmHg  
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What is venous PO2 and PCO2 amounts?   show
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With PO2 100 mmHg - arterial blood is ___ % saturated?   show
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show PCO2, temp, H+ - They decrease hemoglobin's affinity for oxygen  
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How is CO2 transported in blood?   show
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show Heme group  
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show Amino acids  
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show Carbon monoxide  
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show True  
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What is the function of carbonic acid bicarbonate in the blood?   show
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How do buffers act - When the pH is going down?   show
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How do buffers act - When the pH is going up?   show
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show Deep, rapid breathing - trying to flush out CO2  
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show Shallow, slow breathing - trying to accumulate CO2  
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show Medulla Oblongata  
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The (ventral/dorsal) respiratory group set the rhythm and drives respiration?   show
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show False - VRG  
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show False - inspiratory  
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Of (CO2, O2, arterial pH), which is the most important in changing the reate and depth of breathing in a healthy person?   show
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show Low O2; Hypoxic drive  
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Sensors responding to chemical fluctuations are called ____?   show
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show Medulla in the brain stem  
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Where are peripheral chemoreceptors located?   show
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Peripheral chemoreceptors are sensitive to which of the three stimuli?   show
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show High CO2  
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show Hypercapnia  
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Hypercapnia results in (increased/decreased) depth & rate of breathing?   show
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PCO2 is the (most/least) powerful stimulus for respiration?   show
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____ - Increased rate and depth of breathing, occurs in response to hypercapnia?   show
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____ - Slow and shallow breathing due to abnormally low PCO2 levels?   show
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Substantial drops in arterial PO2 to ___ mmHg are needed before oxygen levels become a major stimulus to increase ventilation? Why?   show
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People with emphysema and chronic bronchitis, CO2 is not removed and their chemoreceptors become unresponsive to ____? What is this called?   show
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People that respond to hypoxic drive, what is their primary respiratory stimulus?   show
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(T/F) - Hering-Breuer prevents lung over inflation?   show
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