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Autonomic Innervation, Hormones, Drugs

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Question
Answer
Where does the ANS innervate for the control of contraction?   exerted on SA and/or AV Nodes  
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Which division of the ANS is normally dominant?   Parasympathetic  
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What Neurotransmitter & receptor type does the Parasympathetic use?   Acetylcholine - Cholinergic receptors  
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What effect does Acetylcholine have on RP?   Hyperpolarize  
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What is the function of the Parasympathetic?   REDUCES HR and Contractility  
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What is the significance of the Parasympathetic on the heart?   HYPERPOLARIZES Cardiac RP via  
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Where do Sympathetic impulses come from?   Thoracic Nerve Branches  
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Where do Parasympathetic impulses come from?   Vagus Nerve  
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Where does the Neurotransmitter Epinephrine come from?   Adrenal Glands  
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What are the 2 receptors that accept Epinephrine?   ß-1 and ß2  
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What is the result of Epinephrine binding to a ß-1 receptor?   DEPOLARIZATION --> INCREASE Rate/Force of Contraction  
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What is the result of Epinephrine binding to a ß-2 receptor?   HYPERPOLARIZATION --> Vasodialation  
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What 3 factors influence HR?   Drugs, Hormones, ANS  
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What are the 2 types of Drugs which effect the control of contraction?   Cholenergic blockers & ß-blockers  
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What type of blocker is Atropine, and how does it work?   Cholenergic - blocks Acetylcholine --> blocks Parasympathetic -->  
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How do ß-blockers work?   blocks ß-1 --> cancel Noerepinephrine --> DECREASE HR/BP  
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What is the Neurotransmitter used by the Sympathetic NS?   Norepinephrine  
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How does Norepinephrine effect the Heart?   DEPOLARIZES Cardiac RP via ^ Na+/Ca++ Permeability  
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What is the function of the Sympathetic division of the ANS?   INCREASES HR and Contractility  
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Created by: Kristel
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