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Contraction Control

Autonomic Innervation, Hormones, Drugs

Where does the ANS innervate for the control of contraction? exerted on SA and/or AV Nodes
Which division of the ANS is normally dominant? Parasympathetic
What Neurotransmitter & receptor type does the Parasympathetic use? Acetylcholine - Cholinergic receptors
What effect does Acetylcholine have on RP? Hyperpolarize
What is the function of the Parasympathetic? REDUCES HR and Contractility
What is the significance of the Parasympathetic on the heart? HYPERPOLARIZES Cardiac RP via
Where do Sympathetic impulses come from? Thoracic Nerve Branches
Where do Parasympathetic impulses come from? Vagus Nerve
Where does the Neurotransmitter Epinephrine come from? Adrenal Glands
What are the 2 receptors that accept Epinephrine? ß-1 and ß2
What is the result of Epinephrine binding to a ß-1 receptor? DEPOLARIZATION --> INCREASE Rate/Force of Contraction
What is the result of Epinephrine binding to a ß-2 receptor? HYPERPOLARIZATION --> Vasodialation
What 3 factors influence HR? Drugs, Hormones, ANS
What are the 2 types of Drugs which effect the control of contraction? Cholenergic blockers & ß-blockers
What type of blocker is Atropine, and how does it work? Cholenergic - blocks Acetylcholine --> blocks Parasympathetic -->
How do ß-blockers work? blocks ß-1 --> cancel Noerepinephrine --> DECREASE HR/BP
What is the Neurotransmitter used by the Sympathetic NS? Norepinephrine
How does Norepinephrine effect the Heart? DEPOLARIZES Cardiac RP via ^ Na+/Ca++ Permeability
What is the function of the Sympathetic division of the ANS? INCREASES HR and Contractility
Created by: Kristel
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