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amino acids in proteins

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The pKa for alpha-amino groups is   approximately 9.5 (8.8 - 11.0), protonated at pH of 7 with a positive charge.  
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The pKa for alpha-carboxyl groups is   approximately 2 (1.8 - 2.4), mostly dissociated at pH of 7 with a negative charge.  
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alanine   ala  
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arganine   arg  
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asparagine   asn  
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aspartate   asp  
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cysteine   cys  
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glutamate   glu  
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glutamine   gln  
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glycine   gly  
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histidine   his  
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isoleucine   ile  
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leucine   leu  
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lysine   lys  
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methionine   met  
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phenylalanine   phe  
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proline   pro  
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serine   ser  
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theonine   thr  
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tryptophan   trp  
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tyrosine   tyr  
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valine   val  
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Essential AA: Little Valentine Take My Heart, Practicing Love Improves The Art   Leucine Valine Tryptophan Methionine Histidine Phenylaline Lysine Isoleucine Threonine Arginine  
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Nonessential amino acids: Almost All Girls Go Crazy Grabbing Protracted Slug Testicles   Alanine, Asparagine, Glycine, Glutamate, Cysteine, Aspartate, Glutamine, Proline, Serine, Tyrosine  
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Which contain R-groups that are nonpolar, polar?   If an R-group contains an oxygen or a nitrogen, it is polar. If an R-group does not contain oxygen or nitrogen, it is nonpolar.  
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NOnpolar=   No Oxygen or Nitrogen in nonpolar R groups  
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Which R-groups are charged ?   GLAAH- It hurts to be shocked by something with a charge! Glu, Lys, Asp, Arg, His  
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polar groups: Seriously The Tyrone's Ass is Glowing   Ser, Thr, Tyr, Asn, Gln  
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What AA's can form salt bonds?   AG neg, AL pos Aspartic acid, Glutamic acid- neg Arginine, Lysine-pos Histidine is pos when ph>6  
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Aspartic acid pka   4  
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glutamic acid pka   4  
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histidine pka   6  
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lysine pka   10  
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arginine pka   12  
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cysteine pka   8  
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tyrosine pka   8  
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positively charged R groups will be ____ if _____   positive (+1, pka>ph  
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negatively charged R groups will be ____ if ____   negative (-1), ph>pka  
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The charge on the alpha-carboxyl group is neutral if the pH of the solution is ____ and is negative if the pH of the solution is _____.   below 2, above 2  
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The charge on the alpha-amino group is positive if the pH of the solution is _____ and is neutral if the pH of the solution is _____.   below 9.5, above 9.5  
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how to calculate pL   pI = (pKa1 + pKa2)/2 e.g (pka-alpha-amino + pka-alpha-carboxyl)/2 e.g. (pka-alpha-amino + pka-R group)/2  
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go over charges on proteins   in notebook and ch 6 problems  
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AA has a pos charge when   ph of solution<pL  
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AA has a neg charge when   ph of solution>pL  
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What is the charge of histidine below/above pka?   pka=6 ph>pka= neutral-no salt bonds ph<pka= positive  
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