MLT Study Guide
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| What is the specimen(s) for RPR? | show 🗑
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| show | Rapid Plasma Reagin
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| What is the test principle for RPR? | show 🗑
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| What is detected in the specimen for RPR? | show 🗑
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| show | VDRL cardiolipin modified with choline chloride attached to charcoal
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| show | screening
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| show | non-specific
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| show | RPR
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| show | VDRL
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| show | Venereal Disease Reference Laboratory
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| What is the specimen(s) for VDRL? | show 🗑
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| What is the test principle for VDRL? | show 🗑
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| What is detected in the specimen for VDRL? | show 🗑
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| show | cardiolipin, lecithin, cholesterol
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| show | RPR and VDRL
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| Name 3 treponemal tests? | show 🗑
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| Is VDRL used for screening or confirmatory? | show 🗑
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| show | Non-specific except for CSF
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| EIA or immunochemoluminescence: What is the test specimen(s)? | show 🗑
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| show | Enzyme or fluorescence attached to Ab that attaches to Ag
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| show | Ab (IgG and IgM) against T. pallidum
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| EIA or immunochemoluminescence: What Ag is used in the test? | show 🗑
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| EIA or immunochemoluminescence: Screening or confirmatory? | show 🗑
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| EIA or immunochemoluminescence: Specificity? | show 🗑
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| EIA or immunochemoluminescence: What is used to remove antibody to normal flora treponemes which cause false positives? | show 🗑
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| show | diluted, heat inactivated serum
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| FTA-ABS: What is the test principle? | show 🗑
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| show | Ab against T. pallidum
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| FTA-ABS: What Ag is used in the test? | show 🗑
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| FTA-ABS: Screening or confirmatory? | show 🗑
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| show | Specific
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| show | Fluorescent Treponemal Antibody Absorbed
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| show | Primary: low
Secondary: high
L/T: low
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| show | Primary: low
Secondary: high
L/T: low
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| State Sensitivity levels for FTA-ABS: primary, secondary and latent/tertiary syphilis | show 🗑
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| show | Primary: early = low, high
Secondary: high
L/T: high
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| Interpret results- RPR: reactive FTA-ABS: reactive | show 🗑
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| Interpret results- RPR: nonreactive FTA-ABS: reactive | show 🗑
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| show | Negative
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| Interpret results- RPR: reactive FTA-ABS: nonreactive | show 🗑
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| Interpret Results- EIA screen: reactive RPR: reactive: reactive RPR titer: (1:32) | show 🗑
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| show | Treponema pallidum
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| What other best known disease is caused by a spirochete? | show 🗑
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| What is the reservoir for T. pallidum? | show 🗑
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| show | Syphilis
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| show | Yaws
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| What disease does T. endemicum cause? | show 🗑
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| What disease does T. caroteum cause? | show 🗑
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| show | Rabbit syphilis (organism morphologically identical to human spirochete)
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| show | Sexually transmitted (direct contact with lesion)
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| show | False. There is no pus formation in the chancres unless a secondary infection sets in.
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| In the Primary Stage: 30% are positive after ___ week(s) 90% are positive after ___ weeks(s) | show 🗑
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| show | Secondary stage; 100%
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| What are the 3 manifestations for the Tertiary stage? | show 🗑
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| True or False: 1/3 of untreated latent individuals develop tertiary syphilis. | show 🗑
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| show | False. The specimen is observed by dark-field microscopy or fluorescent Ab testing.
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| For VDRL, what is the RPM and minutes? | show 🗑
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| show | 100 rpms fo 8 minutes
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| show | Collagen dz (arthritis, LE), sometimes increased amount of reagin, infectious mononucleosis, malaria, leprosy, pregnancy, measles, drug abuse
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| What are 3 causes of False negatives? | show 🗑
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| What method do you use to test congenital syphilis? | show 🗑
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| show | penicillin. If allergic, doxycycline or tetracycline.
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| show | VDRL
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| At what time are tests non-reactive in the primary stage? | show 🗑
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| At what time are tests non-reactive in the secondary stage? | show 🗑
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| True or False. Perinatal transmission can occur at any time during pregnancy but only the latent stage of the disease. | show 🗑
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| show | spread to lymph nodes and then to blood stream
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| True or False. Syphilis cannot be spread by toilet seats, door knobs, swimming pools, shared clothing, or eating utensils. | show 🗑
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| show | chancre
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| For Treponema pallidum Hemagglutination(TPHA), a button is a positive or negative result? | show 🗑
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| show | Nichol's strain
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| show | Lack of commercial kits, standardization
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Created by:
Nuar
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