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Influences on

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Question
Answer
What influences Enzyme Action?   anything that can change the SHAPE or ELECTRIC CHARGE of an Enzyme can alter its activity  
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What are some Modifiers of Enzyme Action?   Heat, pH  
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How can heat modify an Enzymes Actions?   1. Activation Energy; 2. Denature Enzyme 3-D configuration  
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How can pH modify an Enzymes Actions?   may change Electrical Charge of an Enzyme  
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What are Cofactors?   typically Metals NECESSARY to complete enzyme's Active Site  
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What are some examples of Cofactors?   Mg++, Fe++, Cu++  
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Will an enzyme work if its Cofactor is not present?   No  
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What are Coenzymes?   TRANSFER Atoms to/from a Substrate  
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What are Coenzymes made of?   Organic NON-Protein molecule -or- Water Soluble Vitamins ( B=Complex, C)  
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Name 4 influences on Ezyme Action?   1. Modifiers 2. Cofactors 3. Coenzymes 4. Inhibitors  
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What are the types of Inhibitors?   Competitive, NON-Competitive  
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What are 3 characterisitcs of Competitive Inhibitors?   1. Chemically RESEMBLES Substrate (similar SHAPE); 2. OCCUPIES Active Site of a SPECIFIC Enzyme; 3. usually IRREVERSIBLE  
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Why are Inhibitors produced?   Cells produce Inhibitors - PREVENT Overproduction of certain products - Control Metabolism  
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What are 2 characteristics of NON-Competitive Inhibitors?   1. NO Chemical Similarity to Substrate; 2. mey be Reversible or Irreversible; 3  
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What is Feedback Inhibition?   REVERSIBLE:NON-Competitive Inhibitor - attaches to Regulatory Site = TEMPORARILY altering Enzyme shape  
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When are NON-Competitive Inhbitors Irreversible?   attachment to AA subgroups of the Enzyme PERMANENTLY Denaturing the Enzyme - HEAVY METALS  
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What are 2 examples of Irreversible NON-Competitive Inhibitors?   Mercury, Lead  
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What are the 5 Classes of Enzymes?   1. Hydrolases; 2. Sythases; 3. Dehydrogenases; 4. Phosphatases; 5. Kinases  
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What are 3 examples of Hydrolases?   1. Pepsin 2. Amylase 3. Lipase  
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What is the function of Hydrolase Enzymes?   breakdown substances tih the ADDITION of WATER Molecules  
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How do Hydrolases breakdown substances?   Proteins --> Polypeptides; Carbohydrates --> Simple Sugars; Fats --> Fatty Acids + Glycerol  
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What is the function of Synthetases?   REMOVE Water to JOIN Molecules together  
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What is the function of Dehydrogenases?   REMOVES Electrons and H+  
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What is the function of Phosphatases?   REMOVES Phosphate Groups  
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What is the function of Kinases?   ADDS Phosphate Groups  
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