Phys3 Clear & Transp
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| show | Volume of plasma cleared of a substance per unit time
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| show | 1.Filtration.
2.reabsorption.
3.secretion.
**The amount cleared equals the amount in the urine at that time.
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| show | NET secretion or reabsorption
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| Cx X Px = Ux X V | show 🗑
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| show | Cx = (Ux X V)/Px
**Measured in ml/min, measure the VOLUME of plasma cleared per unit TIME
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| show | O
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| show | Concentrations in Bowman's capsule equal that in the BL plasma.
1.Univalent electrolytes.
2.Urea.
3.Glucose.
4.aa's.
**GFR=(Ux X V)/Px
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| What are some examples of solutes that are not freely filtered? | show 🗑
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| Why is inulin a good indicator of GFR | show 🗑
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| show | YES, if the substance is freely filtered AND is excreted.
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| show | YES, if it is secreted and NONE appears in the renal vein.
**RBF = (U(PAH) X V)/P(PAH)
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| substance with a clearance = RBF | show 🗑
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| If GFR=Clearance | show 🗑
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| show | Net SECRETION
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| show | Net Reabsorption
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| Practical method of measuring GFR | show 🗑
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| show | 1.24 hr patient urine.
2.BL sample during collection time.
3.[creatinine] in both BL & urine.
4.Use clearance formlua.
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| show | YES:
1.Dec muscle mass (elderly and children will appear to have dec GFR).
2.Ingestion of large amount of meat (Inc [creatinine] which will make GFR appear high).
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| show | It DECREASES with every DECADE
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| normal plasma value of creatinine? | show 🗑
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| relationship b/w plasma creatinine and GFR? | show 🗑
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| How will renal disease cause Inc in BUN? | show 🗑
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| using BUN to determine dehydration | show 🗑
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| what happens to the BUN/Creatine ratio with vloume depletion? | show 🗑
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| show | INCREASES it
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| How does a Ded FF affect π(PTC) | show 🗑
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Created by:
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