CMI-Fall 2011
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| What defines acute hepatitis? | show 🗑
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| show | -Sx>6mo
-Risk of progression to fibrosis and cirrhosis,which adds risk of liver CA
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| show | -A severe, potentially fatal form of acute hep.
-Signs of liver failure w/in 4-8wks of onset sx
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| Explain blood supply to and from liver: | show 🗑
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| The liver breaks down toxic products, what is the pathway of breakdown for a certain toxic byproduct of muscle breakdown? | show 🗑
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| show | Fat-soluble to water-soluble
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| Which 2 important hormones that are synthesized from cholesterol are regulated by the liver? | show 🗑
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| What are some symptoms suggestive of acute hepatitis? | show 🗑
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| show | ALT,AST,Alk Phos,GGT
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| What is a NL aminotransferase value? | show 🗑
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| show | >1,000
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| show | -Acetaminophen
-Ischemic
-Unusual virus
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| show | Drugs, ischemia, viruses
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| If AST>ALT, what is the hep from, usually? | show 🗑
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| When do you see Hep D? | show 🗑
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| Routes of transmission of HAV? | show 🗑
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| show | Lifelong immunity (either from past
infection or vaccination)
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| HBV route of transmission? | show 🗑
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| If HebB core AB +? | show 🗑
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| show | Infection
(Acute or chronic-active or passive)
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| IgM anti-HBc? | show 🗑
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| IgG anti-HBc? | show 🗑
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| HBsAG present w/ IgM anti-HBc? | show 🗑
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| show | Appears shortly before sxs
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| show | No exposure
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| show | No infection
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| Neg HBsAb? | show 🗑
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| Pos HBcAg? | show 🗑
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| show | Infection
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| Pos HBsAb? | show 🗑
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| show | Never exposed, never infected, not immune.
*VACCINATE!
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| show | Old infection
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| show | Not exposed, no infection, immune
*Had a vaccination :)
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| show | HIGH INFECTIOUS STATE (replicating the
virus)
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| Anti HCV negative? | show 🗑
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| show | Acute, Chronic, Previous; confirm results w/ RIBA
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| show | Marker of active infection
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| show | Viral load; numerical answer
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| Genotype of HCV? | show 🗑
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| 1/2 of the liver transplants in US are d/t? | show 🗑
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| What is chronic HBV the CHIEF cause of? | show 🗑
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| show | Cirrhosis
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| show | -VACCINATE!!
-HBIG (Hep B immunoglobulin) for exposed individuals
-Testing for surface ag in all pregnant women (to determine if risk to baby)
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| HAV is inactivated and w/o preservatives, who can it be given to? and where is it given? | show 🗑
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| When is Hep B vaccine usually administered? | show 🗑
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| Who is HBvacc rec for? | show 🗑
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| show | -Accelerated combo HAV/HBV vaccine at days
0,7,21
-Booster @ 1 yr
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| What are some of the main causative agents in drug-induced liver injury? | show 🗑
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| show | Acetaminophen poisoning
(>10g; alcohol and malnut enhance risk)
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| show | Females (70-80% of cases)
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| Lab results in autoimmune hep? | show 🗑
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| Tx for autoimmune hep? | show 🗑
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| show | -Inherited d/o of iron metab
-Gene HFE
-MC single gene inherited d/o in US
*IRON OVERLOAD = LIVER INFLAMM
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| show | Transferrin saturation
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| show | Serum ferritin
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| Gold std for dxing HH? | show 🗑
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| What dz involves copper overload? | show 🗑
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| show | -Dz of the young 12-23 y.o. (rare after 40)
-copper deposition (Kaysar-Fleischer rings)
**CONSIDER IN ANY YOUNG PERSON W/LIVER DZ**
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| What is the inherited d/o that can cause lung and liver damage? | show 🗑
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| show | Genotype testing:
MM=NL
ZZ=assoc w/cirrhosis
MZ=assoc w/lung or liver dz
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| What is the MC metabolic indication for liver transplant with excellent outcomes? | show 🗑
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Created by:
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