Parenteral Nutrition
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What is parenteral nutrition? | show 🗑
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what are electrolytes? | show 🗑
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show | -nonfunctioning GIT
-need for Bowel Rest
-severe malnutrition and EN not possible, or inadequate to meet needs
-Patients whose nutrition needs exceed what can be met enterally
-pre-operative repletion of malnourished patients
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contraindications of Parenteral Nutrition Support | show 🗑
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PN | show 🗑
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CPN | show 🗑
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TPN | show 🗑
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PPN | show 🗑
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show | defined by the position of the tip (NOT by the site of entry)
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Components of PN | show 🗑
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Non-tunneled central line | show 🗑
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What are the 2 types of short term CPN? | show 🗑
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show | -central line via peripheral access
-entrance in antecubital vein
-threaded into subclavian vein
-catheter tip in superior vena cava
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show | -IV antibiotic therapy
-Blood
-Meds
-Chemo
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show | -tunneled catheters
-implanted ports
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What is a tunneled catheter? | show 🗑
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How do tunneled catheters decrease risk of infection? | show 🗑
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What is an Implanted Port? | show 🗑
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show | -for short-term
-standard peripheral lines: site rotation every 48-72 hours
-extended dwell catheters: up to 4 weeks
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show | 48-72 hours
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show | -phlebitis
-phlebotomy
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show | -Monohydrate Glucose
-aka Dextrose
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how many kcals are in dextrose monohydrate? | show 🗑
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What are the typical concentrations of Dextrose stock solutions? | show 🗑
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What are the typical final dextrose concentrations? | show 🗑
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show | -5 mg/kg/min
-7 mg/kg/min may be tolerated in burns/trauma
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what happens when the Maximum CHO load of typical PN solution is exceeded? | show 🗑
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What is the typical ptotein source in a PN solution? | show 🗑
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show | -may vary in concentration
-8.5% and 10% common
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show | 40-50%
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What % of standard Amino Acid solutions made of Non-essential Amino Acids? | show 🗑
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show | -more Essential Amino Acids
-little to no Non-Essential Amino Acids
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How are Amino Acid compositions different for PN solutions for liver failure? | show 🗑
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What kinds of lipids are found in the typical PN solution? | show 🗑
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How much Essential Fatty acids are in the typical PN solution? | show 🗑
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What is the caloric value of amino acids in TPN solution? | show 🗑
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show | -8.5%
-10% most common
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What is the minimum amount of CHO needed in a TPN solution to prevent endogenous glucose production? | show 🗑
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show | 10 or 20%
-20% more common
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show | -10 kcal/g
-additional kcal is from the glycerol backbone
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what is the maximum amount of lipids that should be given in a TPN solution? | show 🗑
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show | -fatty liver
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show | -gluconate
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show | -prevents blood clots from forming
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What is the benefit of adding pepcid to a TPN solution? | show 🗑
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Why is iron not added to PN solutions? | show 🗑
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How are Structured Triglycerides produced? | show 🗑
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show | -can bypass lymphatic system
-don't require carnitine for transport into mitochondria
-are rapidly oxidized
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show | 8.3 kcal/g
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show | -mostly omega-3 fatty acids
-omega-6
-omega-9
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What are the demonstrated benefits of a Structured Triglyceride PN formula compared to standard lipid emulsions? | show 🗑
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show | -experimental lipid emulsion that is used in Europe, but not approved by FDA in US
-80% olive oil
-20% soybean oil
-ClinOleic is an example
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What are Fish Oil lipid emulsions? | show 🗑
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What is the benefit of using dipeptides containing glutamine for experimental PN solution? | show 🗑
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What is the experimental evidence of benefits of Glutamine? | show 🗑
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What is a "2-in-1" + lipids formulation? | show 🗑
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What is a "Total Nutrient Admixture" (TNA) formulation? | show 🗑
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show | ~650 mOsm/L to prevent phlebitis
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What is the result of too high of osmolarity of a peripheral infusion? | show 🗑
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What are the advantages of peripheral parenteral nutrition? | show 🗑
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show | -osmolarity and volume issues
-maintenance of access (standard IV)
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show | -can accomodate hypertonic solutions
-better for long-term
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What are the disadvantages of central parenteral nutrition? | show 🗑
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kemplea
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