lecture 26 ansari
Help!
|
|
||||
|---|---|---|---|---|---|
| adaptive immune system | show 🗑
|
||||
| show | is non-specific and uses germline receptors like PAMPs and TLRs to catch invading pathogens --> NK cells, dendritic cells, phagocytes, etc. Responsible for the short-lived acute inflammation response
🗑
|
||||
| conductor vs executor of adaptive immunity | show 🗑
|
||||
| type I hypersensitivity reactions | show 🗑
|
||||
| show | describes the tendency of an individual to be prone to type I hypersensitivity reactions, that is mast cell degranulation causing urticaria, etc when exposed to various Ags in environment
🗑
|
||||
| examples of type I hypersensitivity reactions | show 🗑
|
||||
| show | antibody-mediated; Abs bind to EC matrix or RBCs (in hemolytic anemia) with subsequent destruction by opsonization (phagocytosis) or complement activation/lysis
🗑
|
||||
| examples of type II hypersensitivity reactions | show 🗑
|
||||
| show | antiglomerular BM and lung alveolar antibody deposition causes rapidly progressive glomerulonephritis and pulmonary hemorrhage. remember LINEAR PATTERN OF AB AND COMPLEMENT DEPOSITION
🗑
|
||||
| show | mediated by deposition of immune complexes in extravascular sites or vessel walls. injury through complement activation or recruitment of neutrophils or monocytes. formation of immune complexes in the blood is not necessarily abnormal!!
🗑
|
||||
| show | polyarteritis nodosa: Hep B virus antigens;
SLE: Abs against DNA and nuclear proteins;
serum sickness (horse antithymocyte globulin) and arthus rxns
🗑
|
||||
| remember LUMPY-BUMPY pattern of Ab and complement deposition | show 🗑
|
||||
| type IV hypersensitivity reactions | show 🗑
|
||||
| examples of type IV hypersensitivity reactions | show 🗑
|
||||
| systemic lupus erythematosus (SLE) | show 🗑
|
||||
| screening for presence of _______ is the first step to diagnosis SLE | show 🗑
|
||||
| show | anti-dsDNA antibody and anti-Smith antibody
🗑
|
||||
| screening for presence of _______ leads to dx of Sjogren's syndrome | show 🗑
|
||||
| show | anti-Scl-70
🗑
|
||||
| pathogenesis of SLE | show 🗑
|
||||
| show | renal manifestations - deposition of DNA-anti-DNA complexes in glomerulus (class IV, diffuse proliferative GN is worst prognosis)
🗑
|
||||
| show | lymphocytic infiltration and fibrosis of salivary glands and lacrimal glands causing chronic dry eyes and xerostomia; usually associated with other autoimmune dz like SLE or RA (secondary form); ANA usually (+)
🗑
|
||||
| show | abnormal accumulation of fibrous tissue in skin and other organs, either diffuse or limited type; anti-DNA topoisomerase I antibodies (Scl-70) or anti-centromere antibodies
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
sirprakes
Popular Physiology sets