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Administration of blood and blood products

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Question
Answer
Sodium chloride (NaCl) concentration of blood   0.9%  
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Define Hematocrit   A measurement of total blood volume  
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The Hematacrit for men   42 - 52%  
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The Hematacrit for women   37 - 47%  
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The three plasma proteins   Albumin, Globulins, Fibrinogen  
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Plasma proteins that help thicken and maintain blood volume   Albumins  
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Plasma proteins include the antibodies that help protect us from infection   Globulins  
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Plasma protein that functions as a necessary component for blood clotting   Fibrinogen  
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The average blood volume of plasma   2.6L (2600 mL).  
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The average blood volume of RBCs and platelets   2.4L (2400mL)  
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Average total blood volume   5L (5000mL).  
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The average RBC count   4.2 - 6.2 million/mm3  
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How long do RBCs circulate in the body?   4 months  
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Normal hemoglobin level in men   14 - 18 g/dL  
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Normal hemoglobin level in women   12-16 g/dL  
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Vitamins required for RBC production   B12, folic acid, riboflavin (B2), and pryidoxine (B6)  
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What is the average WBC count?   5,000 - 10,000 mm3 of blood  
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What WBCs are the primary phagocytic cells involved in acute inflammatory response?   Neutrophils  
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What WBCs release lysozyme, an enzyme that destroys certain bacteria?   Neutrophils  
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What is the normal value of Neutrophils?   60 - 70%  
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What WBCs play a role in allergic reactions and are effective against certain parasitic worms?   Eosinophils  
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What is the normal value of Eosiniphils?   1-4%  
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What WBCs are essential to the nonspecific immune response to inflammation because of their role in releasing histamine during tissue damage or invasion?   Basophils  
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What WBCs contain heparin, serotonin, and histamine?   Basophils  
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What is the normal value of Basophils?   0.5 - 1%  
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List the Granular leukocytes   The 'phils', Neutrophils, Eosinophils, Basophils  
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What WBCs are responsible for the Antigen-antibody process (i.e. B-cells and T-cells)?   Lymphocytes  
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What is the normal value of Lymphocytes?   20-40%  
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What WBCs primary job is Engulf foreign antigens, bacteria and cell debris?   Monocytes  
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What is the second type of WBC to arrive at the scene of an injury   Monocytes  
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What is the normal value of Monocytes?   2 - 6%  
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What are the smallest cells in the blood?   Thrombocytes  
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What is the life span of thrombocytes?   5-9 days  
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What is the normal platelet count?   150,000 - 400,000 mm3 of blood  
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Smallest of the plasma proteins, which account for 60% of protein in weight   Albumin  
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Where is Albumin synthesized?   The liver.  
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Which blood protein acts as an antibody?   Gamma globulins  
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Which blood proteins are essential for the transportation of lipids and fat soluble vitamins?   Alpha and Beta Globulins  
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What is the largest of the plasma proteins?   Fibrinogens  
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What percentage of protein by weight does fibrinogens make up?   4%  
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Where are fibrinogens synthesized?   The liver.  
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The 'A' blood type contains which antigen and antibodies?   RBCs contain Type A antigen, Plasma contains Type B anti-bodies  
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The 'B' blood type contains which anitgen and antibodies?   RBCs contain Type B antigen, Plasma contains Type A anti-bodies  
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The 'AB' blood type contains which anitgen and antibodies?   RBCs contains both type A and B antigen, Plasma contains neither anti-A or B antibodies  
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Which blood type is the universal recipient?   Type AB  
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The 'O' blood type contains which anitgen and antibodies?   RBCs contain neither type A or B antigen, Plasma contains both anti-A and B antibodies  
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Which blood type is the universal donor?   Type O  
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An examination in which the different kinds of white blood cells are counted and reported as percentages of the total examined or absolute (actual number) is called   A differential white blood cell count (DIFF)  
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What is transfused when whole blood could result in circulatory overload?   Packed RBCs  
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What are some indications for the use of whole blood?   Hemorrhage, Hypovolemic shock  
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What are some indications for the use of fresh whole blood?   Multiple transfusions, Exchange transfusions  
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What blood is transfused in immunosuppressed or hypersensitive PTs?   Deglycerolized/ Washed RBCs  
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What is used for people with clotting deficiencies or who had an overdose of warfarin (Coumadin)?   Fresh Frozen Plasma (FFP)  
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Define Plasma Exchange (Plasmapheresis)   blood drawn off, cleansed, and components returned.  
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What is Cryoprecipitate   fresh-frozen plasma precipitate which contains factors I and VIII.  
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What is used to treat v0n Willebrand’s disease?   Cryoprecipitate.  
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What is the preferred treatment of hemophilia?   Antihemophilic Factor Concentrate.  
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What is used for blood volume expansion in burns, shock, or protein deficiencies?   Fresh Frozen Plasma  
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What product would you expect the physician to order if the client needed an increase in oxygen carrying capacity?   Packed RBCs.  
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When should the consent form be signed?   no more than 72 hours prior to the administration of the transfusion.  
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What must be verified to ensure that the transfusion products match the recipient’s blood?   Blood type and Rh factor.  
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What is an Autologous Transfusion?   Blood drawn from the client weeks before the scheduled procedure.  
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What is the safest blood for the clients use?   Autologous Transfusion (Clients own blood)  
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Why should the IV tubing for the administration of blood products contain a filter?   Prevent infusion of clots.  
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What kind of tubing does a blood administration set use?   Y tubing  
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How soon must blood be used once its drawn from the blood bank?   within 30 minutes.  
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When preparing a RBC bag, how much saline do you let run into it prior to infusion?   50mL  
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What is the initial flow rate of a blood transfusion?   2mL/minute for the first 15 minutes.  
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When do vitals need to be taken on a patient during a blood transfusion?   At the end of the 15 minutes initial flow rate, and every 30 minutes after until transfusion is complete.  
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If a reaction occurs during the transfusion, the blood component may be clamped off and what infused?   Normal Saline  
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What can cause an Acute Hemolytic reaction?   Infusion of ABO-incompatible whole blood, RBCs, or components containing 10 mL or more of RBC destruction.  
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What is the most common reaction to a blood transfusion?   Febrile, non-hemoltyic  
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What causes circulatory overload   fluid administration faster than the circulation can accommodate.  
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What are some clinical manifistations of circulatory overload?   Cough. Dyspnea. Pulmonary Congestion (rales). Headache. Hypertension. Tachycardia. Distended neck veins.  
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What are some clinical manifistations of Sepsis?   Rapid onset of chills. High fever. Vomiting. Diarrhea. Marked hypotension. Shock.  
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How often should vitals be assessed if the patient suffers a transfusion reaction?   Every 5 minutes.  
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What should be obtained and sent to the lab if the patient suffers a transfusion reaction?   Remaining blood and tubing set used during the transfusion. Sample of the patient’s blood per agency protocol. Urine sample from the patient.  
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What is the first thing the LPN should do if a transfusion reaction is suspected?   Immediately stop the transfusion.  
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