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431 Immunology vocab

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Normal serum proteins that increase rapidly as a result of infection, injury, or trauma to the tissues   Acute phase reactant  
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  autoantibody  
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  alloantibody  
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macromolecules that are capable of eliciting formation of immunoglobulins (antibodies) or sensitized cells in an immunocompetent host   antigen  
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the strength with which a multivalent antibody binds a multivalent antigen   avidity  
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a protein or other substance that acts as a chemical messenger to produces chemotaxis   chemotaxin  
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antigenic features of leukocytes that are identified by groups of monocolonical antibody expressing common or overlapping activity   clusters of differentiation (CD)  
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chemical messenger produced by stimulated cells cells that affects the function or activity of other cells   cytokine  
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the key portion of the immunogen against which the immune response is directed; also known as the determinant site   epitope  
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a simple chemical group that can bind to antibody once it is formed but that cannot stimulate antibody formation unless tied to a larger carrier molecules   hapten  
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a vasoactive amine released from mast cells and basophils during an allergic reaction   histamine  
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a heighten state of immune responsiveness   hypersensitivity  
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the condition of being resistant to infection   Immunity  
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any substance that is capable of inducing an immune response   Immunogen  
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the study of the reactions of a host when foreign substances are introduced into the body   immunology  
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cellular and humor mechanisms involved in the overall reaction of the body to injury or invasion by an infectious agent   inflammation  
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Cytokines produced by T cells and other cell lines that inhibit viral synthesis or act as immune regulators   interferons  
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cytokines or chemical messengers produced by leukocytes that affect the inflammatory process through an increase in soluble factors or cells   interleukins  
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a molecule that binds to a specific receptor   ligand  
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  lymphokines  
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  lyoszyme  
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the genes that control expression of a large group of proteins originally identified on leukocytes but now known to be found on all nucleated cells in the body. These proteins regulate the immune response and play a role in graft rejection   Major Histocompatibility complex (MHC)  
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Serum proteins that attach to foreign substance and enhance phagocytosis   Opsonins  
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the engulfment of cells or particulate matter by leukocytes, macrophages, or other cells   phagocytotis  
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a transformed B cell that actively secretes antibody   plasma cell  
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lack of visible reaction in an antigen antibody reaction caused by an excess of antigen   postzone  
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lack of visible reaction in antigen-antibody combination caused by the presence of excess antibody. This may result in false negative reaction   prozone  
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a type III hypersensitivity reaction that results from the buildup of antibodies to animal serum used in passive immunization   serum sickness  
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the change of a serological test from negative to positive as a result of developing the measurable antibodies in response to infection or immunization   seroconversion  
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