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431 Immunology vocab

Normal serum proteins that increase rapidly as a result of infection, injury, or trauma to the tissues Acute phase reactant
macromolecules that are capable of eliciting formation of immunoglobulins (antibodies) or sensitized cells in an immunocompetent host antigen
the strength with which a multivalent antibody binds a multivalent antigen avidity
a protein or other substance that acts as a chemical messenger to produces chemotaxis chemotaxin
antigenic features of leukocytes that are identified by groups of monocolonical antibody expressing common or overlapping activity clusters of differentiation (CD)
chemical messenger produced by stimulated cells cells that affects the function or activity of other cells cytokine
the key portion of the immunogen against which the immune response is directed; also known as the determinant site epitope
a simple chemical group that can bind to antibody once it is formed but that cannot stimulate antibody formation unless tied to a larger carrier molecules hapten
a vasoactive amine released from mast cells and basophils during an allergic reaction histamine
a heighten state of immune responsiveness hypersensitivity
the condition of being resistant to infection Immunity
any substance that is capable of inducing an immune response Immunogen
the study of the reactions of a host when foreign substances are introduced into the body immunology
cellular and humor mechanisms involved in the overall reaction of the body to injury or invasion by an infectious agent inflammation
Cytokines produced by T cells and other cell lines that inhibit viral synthesis or act as immune regulators interferons
cytokines or chemical messengers produced by leukocytes that affect the inflammatory process through an increase in soluble factors or cells interleukins
a molecule that binds to a specific receptor ligand
the genes that control expression of a large group of proteins originally identified on leukocytes but now known to be found on all nucleated cells in the body. These proteins regulate the immune response and play a role in graft rejection Major Histocompatibility complex (MHC)
Serum proteins that attach to foreign substance and enhance phagocytosis Opsonins
the engulfment of cells or particulate matter by leukocytes, macrophages, or other cells phagocytotis
a transformed B cell that actively secretes antibody plasma cell
lack of visible reaction in an antigen antibody reaction caused by an excess of antigen postzone
lack of visible reaction in antigen-antibody combination caused by the presence of excess antibody. This may result in false negative reaction prozone
a type III hypersensitivity reaction that results from the buildup of antibodies to animal serum used in passive immunization serum sickness
the change of a serological test from negative to positive as a result of developing the measurable antibodies in response to infection or immunization seroconversion
Created by: jnwells03