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Quick Absite review

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show Inhibits cell wall synthesis Altered cell wall (unable to bind)  
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What is the mechanism of quinolones?   show
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What is the mechanism of amphotericin   show
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Which antibiotics are bacteriocidal, with irreversible binding to 30S ribosome subunit, and resistance due to decreased active transport?   show
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show Chromium  
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show Zinc  
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What vitamin deficiency causes weakness (respiratory) and encephalopathy?   show
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What vitamin deficiency causes anemia and neutropenia?   show
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What two electrolyte abnormalities cause hyperexcitability (increased reflexes, tetany)?   show
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What phase of the cell cycle is most sensitive to radiation therapy?   show
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show stimulates fibroblasts and chemotactic for neutrophils (too much/too long can cause fibrosis)  
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show Attracts fibroblasts and increases smooth muscle to speed matric deposition and collagen formation  
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show Portal vein posterior to CBD (on R) and hepatic artery (on L)  
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What is Diabetes Insipidus?   show
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show Increased ADH release most often by head trauma/tumors or SCLC. Oliguria, high urine osmolarity, low serum osmolarity/Na  
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What three fractures are prone to compartment syndrome?   show
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What are the signs of gastrinoma?   show
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What are the symptoms of a somatostatinoma?   show
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show diabetes glossitis stomatitis necrolytic migratory erythema (presenting problem in 70%) Rx = streptozocin/doxorubican (selectively destroy alpha cells) and octreotide (inhibits release)  
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show WDHA syndrome = watery diarrhea hypokalemia achlorydia  
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What other abnormalities can a patient with a tracheoesophageal fistula have?   show
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show Congenital abd wall defect, intrauterine rupture of umbilical cord, no associated defects, lateral (right) defect, no sac  
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show midline defect, may contain liver or other non-bowel contents, frequent anomalies, has peritoneal sac.  
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show hyperaldosteronism = 80% adenoma, 20% bilateral hyperplasia - HTN, low K, high Na  
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What is Addison's disease?   show
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show Excessive secretion of ACTH from the anterior pituitary, usually from a pituitary adenoma. Causes 70% of non-iatrogenic Cushing's syndrome.  
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show hormone disorder with high levels of cortisol - symptoms include characteristic weight gain (truncal obesity, moon face, buffalo hump), purple striae, hirsutism, polyuria, htn, insulin intolerance  
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show Bitemporal hemianopsia - vision missing in outer half of both right and left visual fields  
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show Prolactinoma - galactorrhea, irregular menses  
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What type of cancer demonstrates "peripheral palisading" of nuclei and "retraction artifact"   show
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show venous thrombosis  
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What type of melanoma has the best prognosis? worst prognosis?   show
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What is MALT a precursor to?   show
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show PTU, Propanolol, Prednisone (& other steroids) and methimazole  
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What is MEN I?   show
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What is MEN IIa?   show
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show Thyroid, adrenal, mucosal neuromas/marfan  
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show 6MP derivative, purine analog that acts as an antimetabolite, decreases DNA synthesis  
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show Calcineurin inhibitor - inhibits mRNA encoding of IL-2  
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What is the mechanism of mycophenolate (cellcept)?   show
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show Calcineurin inhibitor - blocks IL-2 expressions/production from T cells - more potent than cyclosporine  
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show blocks IL-1 from macrophages  
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What is the mechanism of sirolimus (Rapamune)?   show
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show reduces FEV1 and FRC  
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What are the effects of PEEP on the lungs?   show
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show air in lungs after normal exhalation  
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What is inspiratory capacity?   show
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What is vital capacity?   show
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What are the characteristics of silvadene?   show
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show painful, can cause acidosis due to carbonic anhydrase inhibition  
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What are the characteristics of silver nitrate?   show
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show Seizures  
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What are side effects of aminoglycosides?   show
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show produces oxygen radicals that breakup DNA  
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What are side effects of metronidazole?   show
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show Niacin - this syndrome is called Pellegra  
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What vitamin deficiency causes dermatitis, hair loss, and thrombocytopenia?   show
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show >1 = lipogenesis (overfeeding); <0.7 = ketosis and fat oxidation (starving)  
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