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Carbohydrates part 2

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Question
Answer
Genetic Defects in Metabolism   1. Glycogen Storage Disease 2. Galactosemia -syndrome in infants where they fail to thrive  
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Methods of Measurement   1. Reducing Methods-glucose is a reducing sugar and will reduct agents to form and end product 2. Enzymatic-measurement of hydrogen peroxide can be measured by slide reaction  
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Trinder Reaction   Coupled reaction Dye colored is proportional to glucose  
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Hexokinase   uses G6P to convert NADP to NADPH is proportional to amount of glucose  
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What is most used Glucose oxidase or Glucose Hexokinase?   Glucose oxidase  
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Fasting Glucose   Normal range- 70-99 mg/dL Impaired range- 100-125 mg/dL Diabetes- 126 mg/dL or higher  
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Self Monitoring Glucose   Type 1- 3-4 times a day Type 2- 1-2 times a day  
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2 Hour Post Prandial Test   75g glucose solution is given 2 hours later glucose level is drawn if >200mg/dL additional testing is preformed  
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Glycemic Control   Doctors can check how patients have been dieting for at least 3 months  
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Ketone Methods   1.Colormetric (Gerhardts and Sodium niroprusside 2.Enzymatic (Beta-hydroxybutryrate dehydrogenase)  
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Microalbumin   elevated glucose causes diabetic renal nephropathy early signs are proteins in urine normal 20-300mg/day  
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Diagnosis of Abnormalities   1. Islet Autoantibody Testing 2. Insulin Testing  
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C-Peptide   Proinsulin- secreted by b-cells precursor to insulin  
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C-Peptide   Corrects insulin structure High insulin=High C-Pep  
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Endogenous C-Peptide   Inside Body High Insulin High C-Peptide  
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Exogenous C-Peptide   Injected in the body High Insulin C-Peptide doesn't increase C-Peptide not contained in Exogenous insulin  
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