Carbohydrates part 2
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Genetic Defects in Metabolism | 1. Glycogen Storage Disease
2. Galactosemia -syndrome in infants where they fail to thrive
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Methods of Measurement | 1. Reducing Methods-glucose is a reducing sugar and will reduct agents to form and end product
2. Enzymatic-measurement of hydrogen peroxide can be measured by slide reaction
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Trinder Reaction | Coupled reaction
Dye colored is proportional to glucose
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Hexokinase | uses G6P to convert NADP to NADPH is proportional to amount of glucose
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What is most used Glucose oxidase or Glucose Hexokinase? | Glucose oxidase
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Fasting Glucose | Normal range- 70-99 mg/dL
Impaired range- 100-125 mg/dL
Diabetes- 126 mg/dL or higher
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Self Monitoring Glucose | Type 1- 3-4 times a day
Type 2- 1-2 times a day
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2 Hour Post Prandial Test | 75g glucose solution is given
2 hours later glucose level is drawn
if >200mg/dL additional testing is preformed
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Glycemic Control | Doctors can check how patients have been dieting for at least 3 months
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Ketone Methods | 1.Colormetric (Gerhardts and Sodium niroprusside
2.Enzymatic (Beta-hydroxybutryrate dehydrogenase)
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Microalbumin | elevated glucose causes diabetic renal nephropathy
early signs are proteins in urine
normal 20-300mg/day
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Diagnosis of Abnormalities | 1. Islet Autoantibody Testing
2. Insulin Testing
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C-Peptide | Proinsulin- secreted by b-cells
precursor to insulin
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C-Peptide | Corrects insulin structure
High insulin=High C-Pep
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Endogenous C-Peptide | Inside Body
High Insulin
High C-Peptide
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Exogenous C-Peptide | Injected in the body
High Insulin
C-Peptide doesn't increase
C-Peptide not contained in Exogenous insulin
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Created by:
nccrevier
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