Immunology Questions Medical Laboratory Science Multiple Choice
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| Which 2 are common to both RNA and DNA? a) exists primarily as single-stranded molecule. b) consists of sugar, phosphate reside, and a purine or pyrimidine base. c) contains pyrimidine and uracil. d) linked by phophodiester bonds | b)consists of sugar, phosphate reside, and a purine or pyrimidine base.
d) linked by phophodiester bonds
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| 12 weeks after onset of the disease, pt with uncomplicated acute hep B usually will demonstrate what in their serum? a) HBsAg b) Anti-HTLV c) Anti-HBe d) Anti-HIV | c) Anti-HBe
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| Define hapten: a) a carrier molecule for an antigen that is not an antigen alone b) a nonimmunogenic material capable of stimulating an immune response only when bound to a carrier protein c) an Ig functional only in the presence of complement | b) a nonimmunogenic material capable of stimulating an immune response only when bound to a carrier protein
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| The rheumatoid factor in rheumatoid arthritis is primarily which type of Ig? a) IgM b) IgG c) IgA d) IgD | a) IgM
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| Light chains of Ig can be comprised of? a) alpha or beta b) alpha or lambda c) kappa or lambda d) kappa or beta | c) kappa or lambda
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| Corneal tissue may be transplanted successfully from one PT to another because: a) the absence of class II transplantation antigens b) the cornea is non-antigenic c) anti-corneal antibodies are easily suppressed d) corneal antigens dont activate Tcell | a) the absence of class II transplantation antigens
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| What is the half life of IgG? a) 2-3 days b) 1-3 days c) 7 days d) 23 days | d) 23 days
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| Which is responsible for causing graft-versus-host reactions? a) lymphocytes b) monocytes c) granulocytes d) platelets | a) lymphocytes
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| What class of Ig is able to agglutinate RBCs after anti-human globulin is added? a) IgG b) IgA c) IgM d) IgE e) IgD | a) IgG
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| The prozone effect, when performing a screening titer, is most likely to result in: a) false positive b) false negative c) no reaction d) mixed reaction | b) false negative
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| Which assay is most helpful in identifying specific allergens? a) RAST b) RIA c) CRP d) complement fixation | a) RAST
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| What part of the Ig molecule is responsible for the different classes? a) Fc b) Fab c) heavy chains d) light chains | c) heavy chains
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| What disease is suspected with these findings? Total Protein=8.4 gm/dL | ANA >1:2560 speckled | CRP = pos | C3 = 30 | C4 = 5 a) scleroderma b) Sjogren's syndrome c) SLE d) rheumatoid arthritis | c) SLE
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| What mediator is released during Tcell activation? a) serotonin b) lymphokines c) thymosin d) Ig e) cytoplasmic granules | b) lymphokines
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| Which of the following genes initiate synthesis of DNA, promote cell division, and inhibit cell death? a) proto-oncogenes b) tumor suppressor genes c) oncogenes d) levi | a) proto-oncogenes
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| HLA-A and HLA-B antigens can be detected using which of the following techniques? a) standard crossmatch b) immunofluorescent staining c) lymphocyte cytotoxicity d) mixed lymphocyte cultures | c) lymphocyte cytotoxicity
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| T or F: The DNA strand ending with a phosphate group is the 5' end. | True
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| What reaction occurs when an insoluble antigen is mixed with its specific antibody? a) precipitation b) agglutination c) sensitization d) fixation | b) agglutination
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| What reaction occurs when a soluble antigen is mixed with its specific antibody? a) precipitation b) agglutination c) sensitization d) fixation | a) precipitation
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| Which is not considered one of the systemic autoimmune rheumatic diseases? a) Systemic lupus erythematosus b) Systemic sclerosis c) Rheumatoid arthritis d) Hashimoto disease | d) Hashimoto disease
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| What temp is optimal for Taw polymerase activity? a) 20 degrees C b) 37 degrees C c) 72 degrees C d) 95 degrees C | c) 72 degrees C
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| In skin tests for an allergy, a wheal and flare development indicates what? a) immediate hypersensitivity b) delayed hypersensitivity c) anergy d) arthus reaction | a) immediate hypersensitivity
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| What is the "gold standard" for ANA detection a) RIA b) ELISA c) lateral flow immunoassay d) slide-base IFA | d) slide-base IFA
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| A cause of false-positive results in RPR test for syphilis is: a) strep infection b) staph infection c) HIV d) infectious mono | d) infectious mono
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| Phagocytosis is greatly enhanced by: a) hemolysins b) opsonins c) haptens d) antitoxins | b) opsonins
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| Which nitrogenous base is present in DNA but not in RNA? a) guanine b) cytosine c) adenine d) thymine | d) thymine
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