Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| Process of removing the antibody from serum sample | Adsorption
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| Force of attraction beteeen 1 Fab and 1 epitope | Affinity
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| 1 or 2 or more different genes that may occupy a specific locus on a chromosome | Allele
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| Special class of immumogen that induces hypersensitivity reaction | Allergen
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| Gene that does not produce a detectable product | Amorph
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| Any substance Protein or nonprotein that when introduced into an animal causes production of an antibody | Antigen
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| Aggregates of histiocytes are seen in acute rheumatic fever | Aschoff Bodies
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| An antibody produced in response to an antigen possessed by the same individual | Autoantibody
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| Antigenic substance found within the same individual | Autologous
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| Sum of all attractive forces between a multivalent antibody to a multivalent antigen | Avidity
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| Thermolabile protein present in normal animal serum | Complement
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| Genetic combination where both genes at a single loci are expressed | Codominant
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| Characteristic of an antibody to react stronger with cells that have a homozygous presentation of an antigen | Dosage
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| Discovered the process of vaccination | Edward Jenner
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| Process used to remove antibodies bound to RBCs | Elution
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| Ratio of antigen dilution to antibody dilution at which maximum precipitation occurs | Equivalence Zone
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| Total genetic composition of an individual, representing maternally and paternally derived genes | Genotype
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| Acting like an antigen when coupled with a protein carrier but incapable by itself of stimulating antibody formation | Hapten
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| Portion of immunoglobulin molecule important for maintaining the correct orientation of the arm of the antibody in relation to its binding with the antigen | Hinge region
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| Any substance that can induce an immune response (not necessarily Ab production) | Immunogen
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| Subtype of immunoglobuli classes | Isotype
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| Immune competent cells | Lymphocytes
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| Substances that are produced by activated T lymphocytes that participate in various cell mediated immunity | Lymphokines
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| Antigen presenting or processing cell | Macrophage
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| Blood transfused is equal to recipient's blood volume | Massive Transfusion
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| Area in the lymph node where the plasma cells predominate when a state of localized infection occurs | Medulla
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| Substance in serum that promotes immune adherence and facilitates phagocytosis by the reticuloendothelial system | Opsonin
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| Immunologic procedure in whoch antibody and antigen are placed in wells of a gel medium plate and allowed to diffuse in order to visualize the reaction by a precipitin line | Ouchterlony
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| Detectable or expressed characteristics of genes | Phenotype
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| Immediate precusor of antibodies | Plasma cells
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| Phenomenon of antigen excess | Postzone
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| Responsible for the flexibility of the hinge region of the immumoglobulin | Proline
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| Phenomenon of antibody excess | Prozone
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| "Stack of coins" appearance of red cells | Rouleaux Formation
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| Measure of the strength of an antibody by testing its reactivity at increasing dilutions against the appropeiate antigen. The reciprocal of the highest dilution that shows agglutination. | Titer
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| Substances added to an immunogen to enhance immune response by: -prolonging retention time -increasingthe effective size of immunogen -stimulating the influx of macrophages and/or lymphocytes | Adjuvants
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| A.) Monomer; predominant/highest concentration Ab in immune serum globulin preparation due to having the longest half life; responsible for 2ndary (anamnestic) immune response;associated with HLA B.) 4 Isotypes of this Immunoglobulin Subclass | A.) IgG
B.) 1, 2, 3, 4
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| Function of IgG: A.) Provide immunity to the newborn 1.) isotype/s cross placenta 2.) best isotype B.) Best in complement activation C.) Best in agglutination D.) Best in precipitation | A.1. All except IgG2
A.2. IgG1
B. IgG3 > IgG1 > IgG2
C. IgM
D. IgG
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| Monomer (serum IgA) and dimer (secretory IgA); associated with transport piece of secretory component produced by epithelial cells near IgA producing Ab plasma cells which functions to prevent enzymatic degradation of IgA; Ab found in secretions; | IgA
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| Most common antibody deficiency | IgA
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| Pentamer; responsible for 1° immune response, neutralization of toxins & viruses, opsonization & agglutination reactions; best in complement activation; | IgM
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| May be present in amniotic fluid if there is infection; first to appear in the surface of B-cell; first produced by an infant; destroyed by sulfhydryl compounds: DTT & 2-ME that target disulfide bonds of J chain | IgM
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| Abundant in immunocompetent but unstimulated B-cells; second to appear in B-cell; has activity against penicillin & insulin | IgD
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| IgD main function | Immunoregulation
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| Has reaginic activity and affinity to mast cells and basophils causing release of histamine; increased in parasitic infections, allergic/anaphylactic reactions | IgE
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Created by:
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