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Bone tumors

        Help!  

Type
Description
Location
Incidence
Special things to remember
Endochondroma   Cartilaginous neoplasm in intermedullary bone   Distal extremities (hands and feet)   no special age    
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Osteoblastoma   Similar to osteoid osteoma (interlacing traveculae of woven bone surrounded by OB but larger   vertebral column   None    
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Osteoid osteoma   Interlacing traveulae of woven bone surrounded by osteoblasts (proliferation of osteoid and fibrous tissue)   Near end of diaphysis of the femur or tibia   Males under <25    
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Osteoma   Dense bone maturation (new piece of bone grows on another piece   Skull/facial bones; often protrudes into paranasal sinus   Males of any age    
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Osteosarcoma (name predisposing factors)   osteoid and bone-producing neoplasm; Codman's triangle, sunburst pattern, increase ALP   Distal femur, metaphysis of long bones, proximal tibial region (knee)   Males 10-20   Predisposing factors: Paget's, bone infarcts, radiation, familial retinoblastoma; early hematogenous spread to liver, lungs, brain  
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Ewing's sarcoma   Anaplastic "small blue cell" tumor. Onion skin appearance in bone.   Diaphysis oflong bones, pelvis, scapula, ribs   Males < 15   translocation 11;22;responsive to chemo but aggressive with early mets; in early stages may look like acute osteomyelitis  
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Chondrosarcoma   cartilaginous tumor. Expansile glistening mass within the medullary cavity   pelvis, spine, scapula, humerus, tibia, femur   Males 30-60   May have come from an osteochondroma  
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Osteochondroma (aka ___)   Exostosis. Cartilage-capped projection from under periosteum   Long metaphysis: distal femer, proximal tibia (knee)   Male <25 years old   Most common benign tumor; rarerly turns into a chondrosarcoma  
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Giant cell tumor (aka _____)   osteoclastoma. locally aggressive tumor with spindle-shaped cells with multi-nucleated gian cells; soap bubbles, double bubble appearance on X-ray   Epiphyses of long bones (knee is common)   Females 20-40    
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