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Bone tumors

TypeDescriptionLocationIncidenceSpecial things to remember
Endochondroma Cartilaginous neoplasm in intermedullary bone Distal extremities (hands and feet) no special age
Osteoblastoma Similar to osteoid osteoma (interlacing traveculae of woven bone surrounded by OB but larger vertebral column None
Osteoid osteoma Interlacing traveulae of woven bone surrounded by osteoblasts (proliferation of osteoid and fibrous tissue) Near end of diaphysis of the femur or tibia Males under <25
Osteoma Dense bone maturation (new piece of bone grows on another piece Skull/facial bones; often protrudes into paranasal sinus Males of any age
Osteosarcoma (name predisposing factors) osteoid and bone-producing neoplasm; Codman's triangle, sunburst pattern, increase ALP Distal femur, metaphysis of long bones, proximal tibial region (knee) Males 10-20 Predisposing factors: Paget's, bone infarcts, radiation, familial retinoblastoma; early hematogenous spread to liver, lungs, brain
Ewing's sarcoma Anaplastic "small blue cell" tumor. Onion skin appearance in bone. Diaphysis oflong bones, pelvis, scapula, ribs Males < 15 translocation 11;22;responsive to chemo but aggressive with early mets; in early stages may look like acute osteomyelitis
Chondrosarcoma cartilaginous tumor. Expansile glistening mass within the medullary cavity pelvis, spine, scapula, humerus, tibia, femur Males 30-60 May have come from an osteochondroma
Osteochondroma (aka ___) Exostosis. Cartilage-capped projection from under periosteum Long metaphysis: distal femer, proximal tibia (knee) Male <25 years old Most common benign tumor; rarerly turns into a chondrosarcoma
Giant cell tumor (aka _____) osteoclastoma. locally aggressive tumor with spindle-shaped cells with multi-nucleated gian cells; soap bubbles, double bubble appearance on X-ray Epiphyses of long bones (knee is common) Females 20-40
Created by: ddecampo