RISE 2016 TQs
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| Do all patients with cirrhosis with elevated INRs need plasma transfusion? | No. They also have a diminished amount of anti-coagulant proteins. They live in a new equilibrium.
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| An antibody ID panel of a 43YOWF is positive in every cell. Autocontrol is negative. DTT is used to treat the panel cells. All cells are now non-reactive. The most likely antibody from this list is: e, Jk3, Kpb or U | Kpb. Kell antigens are destroyed by DTT
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| Narcolepsy is associated with this HLA molecule | DQ6
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| Mitigation strategies for TRALI | 1. male only plasma products or never pregnant females
2. HLA antibody testing of females with h/o pregnancy
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| Best candidates for perioperative autologous donations | 1. rare blood types
2. multiple alloantibodies
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| What is the maximum storage time and temperature for blood collected in the OR as part of acute normovolemic hemodiution process? | 8 hours and room temp
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| In a patient with anti-e, how many units of ABO compatible blood with need to be screened to provide 3 units for transfusion? | 150
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| Who needs blood: 1. 42YOWM with liver failure, no bleeding today, INR 10. 2. 42YOWM in MVA with pulse of 150 and systolic BP of 60, INR of 1, HCT 40% | 2
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| Formula for Corrected Count increment for working up platelet refractoriness | increment x BSA/plt count in bag
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| Incarceration for more than 72 consecutive hours results in this length of deferral for blood donors | 12 months
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| Cryoprecipitate contains this amount of fibrinogen and factor VIII | 150 mg and 80 IU
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| Which antibody class is most effectively removed by plasmapheresis? A. Patient with IgG multiple myeloma B. Patient with Waldenstrom's macroglobinemia C. Patient with IgA multiple myeloma | B
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| 4 factor PCC can be used to reverse warfarin in bleeding patients. When might it be contraindicated? | h/o thrombosis in the last 90 days
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| HSCT patient typed as O positive. He needs a RBC transfusion the week before his transplant from an A donor. What product do you select? | O cells
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| HSCT patient typed as O positive. He needs a RBC transfusion the week after his transplant from an A donor. What product do you select? | O cells
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| describe major ABO incompatibility in HSCT setting | Donor red Cells infused are lysed by recipient plasma antibodies.
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| describe minor ABO incompatibility in HSCT setting | Red cell Antibodies in donor plasma infused lyse recipient cells
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| What is the specificity of the antibody in Paroxysmal cold hemoglobinuria? | anti-P
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| Anti-P1 can be neutralized by using these | hyatid cyst fluid and/or pigeon egg
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| Calculate the Rhogam dose for a patient with 2% Fetal cells on KB test | 4
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| How long do you store a patient sample and unit segment specimen after RBC transfusion? | 7 days, refrigerated
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| Best platelet product for leukemic patient | irradiated, leukoreduced, apheresis unit, ABO compatible
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| Most frequent antibody specificity in NAIT | anti- HPA1a
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| How is cryoprecipitate made? | Thaw a bag of FFP at 1-6 degrees. Centrifuge. Collect supernatant.
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| Volume of cryo | 15 ml
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| Why are do we ask donors about living/travel to Europe? | vCJD risk
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| How much blood can we collect per kg of donor weight? | 10.5ml of all blood collected per kg of weight
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| How do you differentiate a vasovagal reaction from hypovolemia? | Bradycardia in VV; tachycardia in hypovolemia
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| What is required regarding ABO and Rh testing for a unit shipped to your hospital? | Must confirm ABO type and all Rh D negative units. No weak D required.
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| When can you use therapeutic phlebotomy units in your allogeneic supply? | When all other collection criteria are met and the diagnosis is hereditary hemochromatosis and testosterone replacement therapy . Also you could label with disease but no one would take it into inventory
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| Number of times a plateletpheresis donor can donate per year | 24 times a year; can donate twice in a week; interval between donation should be at least 2 days.
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| What are the "labeling requirements?" | 1. labeled at bedside 2. Two independent patient identifiers 3. date 4. indelible 5. phlebotomist (mechanism to id)
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