Antibacterial agents
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| Antibiotics, group I -Microorganisms, subgroup -Actinomyces (antifungal). Name classes of antibiotics. | 1, Imidazoles
2, Different
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| Antibiotics, group II -Fungi. Side effects. | Allergy, may lead to: anafylactic shock, skin rash, serum sickness, fever, nephritis.
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| Streptomycin -side effect. | Could lead to permanent damage of the auditory nerve -> Hearing loss.
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| Tetracyclines -side effects. | 1, Antibiosis -> Candidosis
2, Hepatic- and kidney damage
3, Brown discoloration of teeth (in children)
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| Chloramphenicol -side effects. | Bone marrow suppression, leading to Aplastic anemia.
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| Name antibiotics that are very toxic to toxic. | Very toxic: Vancomycin.
Toxic products:
1, Nystatin (antifungal)
2, Antitumoral a/b (Actinomycin, Mitomycin, Dactinomycin)
3, Polymixin B, Gramicidin (antibacterial)
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| Generic name of: Penicillin -natural. | 1, Penicillin G
2, Penicillin V
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| Generic name of: Penicillin -semisynthetic | 1, Ampicillin
2, Methicillin
3, Carbenicillin
4, Oxacillin
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| Generic name of: Cephalosporins G1 | 1, Cephalotin
2, Cephazolin
3, Cephapirin
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| Generic name of: Cephalosporins G2 | 1, Cefamandole
2, Cefuroxime
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| Generic name of: Cephalosporins G3 and G4 | 1, Cefotaxime -G3
2, Ceftriaxone -G3
1, Cefpirome -G4
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| Generic name of: Aminoglycosides | 1, Streptomycin
2, Kanamycin
3, Neomycin
4, Gentamycin
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| Generic name of: Tetracyclines | 1, Oxytetracycline
2, Chlortetracycline
3, Tetracycline
4, Doxycycline
5, Minocycline
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| Generic name of: Macrolides | 1, Erythromycin
2, Azithromycin
3, Clarithriomycin
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| Generic name of: Imidazoles | 1, Clotrimazole
2, Miconazole
3, Ketoconazole
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| Generic name of: Different (actinomyces-antibacterial) | 1, Lincomycin
2, Clindamycin
3, VANCOMYCIN
4, Rifamycin
5, Rifampin
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| Generic name of: Different (actinomyces-antifungal) | 1, Nystatin
2, Amphotericin B
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| Generic name of: Different (actinomyces-antitumoral) | 1, Actinomycin
2, Mitomycin
3, Dactinomycin
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| Generic name of: Different (Bacteria-antibacterial) | 1, Polymixin B
2, Bacitracin
3, Gramicinin
4, Mupirocin
5, Colistins
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| Generic name of: Different (human/animal-antibacterial) | 1, Lysozome
2, Erythrin
3, Spermine
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| Generic name of: Different (plant-antibacterial) | 1, Phytoncides
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| Target and mechanism of action for: Penicillin -natural | Narrow spectrum
Gr+
Gr-
Spirochetes
Inhibit CW synthesis
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| Target and mechanism of action for: Penicillin -semisynthetic | Broad spectrum
Inhibit CW synthesis
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| Target and mechanism of action for: Cephalosporins G1 | Good Gr+
Modest Gr-
Inhibit CW synthesis
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| Target and mechanism of action for: Cephalosporins G2 | Good Gr+
Better Gr-
Inhibit CW synthesis
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| Target and mechanism of action for: Cephalosporins G3 | Good Gr-
Modest Gr+
Ps.aeruginosa
Inhibit CW synthesis
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| Target and mechanism of action for: Cephalosporins G4 | Good Gr-
Ps.aeruginosa
Inhibit CW synthesis
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| Target and mechanism of action for: Aminoglycosides | Enteric Gr-
Ps.aeruginosa
Bactericidal effect, inhibit protein synthesis
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| Target and mechanism of action for: Tetracyclines | Very broad spectrum
Gr+
Gr-
Rickettsias and Chlamydias
Bacteriostatic effect
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| Target and mechanism of action for: Chloramphenicol | Broad specturm
Gr+
Gr-
Rickettsias, Chlamydias and anaerobes
Bacteriostatic effect, inhibit protein synthesis
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| Target and mechanism of action for: Macrolides | Narrow spectrum
Gr+
Gr-
Legionella, C.diphteriae, Mycoplasmas, Chlamydias
Bacteriostatic effect, inhibit protein synthesis
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| Target and mechanism of action for: VANCOMYCIN | Very narrow spectrum against multiresistant bacteria.
Bactericidal effect, inhibit CW synthesis
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| Target and mechanism of action for: Rifamycin and Riampin | Narrow spectrum
Gr+ (even multiresistant)
M.tuberculosis
Bactericidal effect, inhibit synthesis of mRNA
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| Target and mechanism of action for: Imidazoles | Broad spectrum antifungals
Candida, dermatophytes and systemic fungal infections.
Interfere w/ sterole synthesis which inhibits cell membrane synthesis, plus anitmetabolic effects.
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| Target and mechanism of action for: Polymixin B | Topical use in wound infections of Gr-
Bactericidal effect, inhibit cell membrane synthesis.
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