TQs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| Product of choice for treating hemophilia A | recombinant factor VIII
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| Recombinant Factor VIII is produced in these cell lines | established hamster cell lines
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| What disease do these products treat?: 1. Humate-P and 2. Alphanate | These products are intended for treatment of von Willebrand's disease
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| What procedures are used to inactivate viruses in Factor VIII products? | nanofiltration, pasteurization and solvent/detergent treatment, and affinity chromatography preparation
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| What infectious agents may escape pathogen inactivation processes in Factor VIII products? | non-lipid enveloped viruses like hepatitis A and parvovirus B19
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| Recombinant Factor IX is produced in these cell lines | Chinese hamster ovary cell lines
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| Product of choice for treating hemophilia B | Recombinant Factor IX
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| Indicated for the urgent reversal of warfarin | 4-factor concentrate (2,7,9,10), Kcentra (vitamin K dependent factors)
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| This product treats ATIII deficiency | Anti-thrombin III concentrate
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| Product of choice for treating or preventing bleeding episodes in patients with inhibitors to Factor VIII or IX | Recombinant factor VII (NovoSeven)
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| Product of choice for treating or preventing bleeding episodes in patients with Glanzmann thrombasthenia | Recombinant factor VII (NovoSeven)
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| These products can be used in Factor XIII deficiency when factor concentrate is not available. | FFP and cryoprecipitate
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| How is albumin manufactured? | Cold alcohol fractionation
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| Method to prevent viral disease transmission in albumin manufacturing process | heated to 60 degrees C for 10 hours
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| % of albumin in a bag of albumin | 96%
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| Composition of "plasma protein fraction" product: __% albumin; __% globulin | 83% and 17%
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| The most common colloid used for volume expansion | HES, hydoxyethyl starch
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| Immune globulins are prepared by cold ethanol fractionation from pools of human plasma from this many donors | 15,000 to 60,000
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| A miscarriage after this Estimated gestational age would require a 300microgram dose of Rhogam | 12 weeks EGA
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| Dose of Rhogam is miscarriage occurs before 12 weeks | 50 microgram
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| A full dose of Rhogam protects against alloimmunization to the D antigen after exposure up to __ mL of D-positive RBCs | 15mL
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