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Hematology in Practice - Chapter 2

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Question
Answer
What is the average M:E ratio for normal adult bone marrow?   4:1  
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The key organs involved in extramedullary hematopoiesis include the:   liver and spleen  
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What assays is the best test to assess the bone marrow's response to anemic stress?   reticulocyte count  
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Antibody-coated red cells that have their antibodies stripped away in the spleen usually reappear in the circulation as:   sperocytes  
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A peripheral blood smear indicator of ineffective bone marrow response to anemia is:   a lack of polychromasia  
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A patient with the following values-- RBC = 4.01 x 10^12/L, Hgb = 12.5 g/dL, and Hct = 37.2% -- will most likely have which of the following RBC indices?   MCV = 92.8 fL, MCH = 31.2 pg, MCHC = 33.6%  
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The hormone responsible for red blood cell development in the bone marrow is:   Erythropoietin  
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What site is the most preferable site for bone marrow aspiration and biopsy in adults?   Iliac Crest  
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A patient's hemoglobin is 12.3 g/dL. On the peripheral smear, the red cells appear normochromic, normocytic. The hematocrit value that correlates with these data is:   37% = 12.3 x 3 = 36.9 (round up)  
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A Wright- stained smear of a patient with an elevated reticulocyte count should show:   Polychromasia  
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When hematopoiesis occurs in the liver in an adult, it is called:   Extramedullary  
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During midfetal life, the primary source of blood cells is the:   liver  
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The CBC parameter that gives insight as to the amount of anisocytosis present in a specimen is:   RDW  
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Patients with moderate anemias (7 to 10 g/dL) may be asymptomatic.   True  
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What are the organs of hematopoiesis in fetal life?   liver and spleen  
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How does the bone marrow respond to anemic stress?   Production is expanded, and red blood cells are released to the circulation prematurely  
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What chemical substances are responsible for differentiation and replication of the pluripotent stem cell?   Cytokines  
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A hormone released from the kidney that is unique for erythroid regeneration is:   Erythropoietin  
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What is the most stable parameter of the CBC?   MCV  
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What one of the red blood cell indices reflects the concentration of hemoglobin per individual red blood cell?   MCHC  
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What formula indicates the correlation check between hemoglobin and hematocrit?   Hgb x 3 = Hct  
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What CBC parameters may provide an indication of anemia before he MCV indicates an overt size change?   RDW  
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What test is the most effective means of assessing red blood cell generation in response to anemia?   Reticulocyte count  
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Created by: Megan Hohenberg
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