Hemostasis
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Pupura | abnormal bleeding.
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| Wiskott-Aldrch syndrome | Smallest platelets seen
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| May-Hegglin anomaly | large platelets
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| Alports syndrome (hereditary) | Giant platelets and thrombocytopenia
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| Bernard-Soulier syndrome | largest platelets seen . Autosomal bleeding disorder, missing platelets glycoproteins
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| Increased utilization of platelets | intravascular coagulation,vascular injury, DIC, Trauma
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| Severe Liver disease | Decreased fibrinogen levels,Prolonged PT
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| Hemophilia A | Inherited. Factor 8 functionally inactive. Impairs coagulation ability. Male sex linked.
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| VonWillebrand Disease | Acquired. Associated with Lupus.prolonged bleeding times.
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| DIC | complication or result of other diseases. d dimer, pt, aptt all increased
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| Antithrombin III | Inhibits thrombin. Protease inhibitor.
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| Heparin Cofactor | inhibits thrombin.
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| Protein C | Major blood coagulation regulatory . Vit k dependent
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| APTT Activated Partial Thromboplastin Time | time required to make thrombin and fibrin polymers. Normal less then 35 sec
Evulates XII,XI,VII,X,V,II and II using intrinsic
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| PT Prothrombin Time | Time required to generate thrombin and fibrin using extrinsic. Thromboplastin and Ca2+. Evulates VII,X,V,II or I
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| INR International Normal Ratio | Standardize the difference in sensitivity of thromboplastin reagents and the effects on PT assays
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| INR Ratio | INR= (PT/mean normal pro time)
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Created by:
Kateskate
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