Rh Blood Group System,Screening, Blood Group Systems
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| Discovery of first Rh antigen | Levine and Stetson.
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| Rh is named after | Rhesus monkeys
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| Genes for ABO antigens are located on | Chromosome #9
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| Genes for D antigen are located on | Chromosome #1
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| What is a Rh Control? | identical to anti-D sera but not antibody.
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| Weak D testing includes | incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times
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| What is Rogam | rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D
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| Discovery of first Rh antigen | Levine and Stetson.
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| Rh is named after | Rhesus monkeys
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| Genes for ABO antigens are located on | Chromosome #9
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| Genes for D antigen are located on | Chromosome #1
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| What is a Rh Control? | identical to anti-D sera but not antibody.
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| Weak D testing includes | incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times
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| What is Rogam | rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D
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| What is 25% albumin used for | reduces zeta potential. allowing rbc to approach each other
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| What does PEG do (polyethylene Glycol) | removes water from test. Most sensitive and most false positives results.
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| Agglutination or Hemolysis at any stage of antibody screen | is a positive result.
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| Most common cold antibodies | anti- N, anti-P and anti I
IgM immediate spin
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| Most common warm antibodies | Rh,Kell, Kidd, Duffy
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| What does it mean if you have a positive auto control? | suggest autoantibody or medication antibody. Usually Lea or Leb
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| What are the dosage antibodies | kidd,dffy,Rh,MNs
Kidds and Duffy the monkey eat M&N
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| Lewis system | antigen made in tissue and secreted into blood. Inheritance depends on both genes and secretor genes.
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| Only in childhood can show this lewis pattern | Le(a+b-) or Le (a+b+)
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| What is the related disease state with Lewis antigens | peptic ulcers and H.Pylori
Tumor formation, transplant failures
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| I Blood system (individuality), at birth is? In adults? | rich in i as infant
rich in I as adult
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| Production of Autoanti-I are associated with what disease states? | Mycopasma pnumoniae and monucleosis
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| M and N antiges are found on | glycoprotein A
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| S and S antiges are found on | glycoprotein B
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| Anti- M is associated with | Burn patients of bacterial infections
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| Cold antibodies (naturally occuring ) are | LiPMAN
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| K | Kell
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| k | cellano
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| KPa | penny
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| KPb | ratenberg
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| Kell is associate with which syndrome | McLeod -muscle and nerve, slow from of muscular distrophy. acanthrocyte prodction.
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| Fy(a-b-) null phenotype- common in blacks in africa can resist | plasmodium
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| Kidd antibodies are common in | HTR
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| Diego is higher in | Asians and South American populations
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| Diego is useful in | mongolian ancestry research
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