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Blood Bank
Rh Blood Group System,Screening, Blood Group Systems
| Question | Answer |
|---|---|
| Discovery of first Rh antigen | Levine and Stetson. |
| Rh is named after | Rhesus monkeys |
| Genes for ABO antigens are located on | Chromosome #9 |
| Genes for D antigen are located on | Chromosome #1 |
| What is a Rh Control? | identical to anti-D sera but not antibody. |
| Weak D testing includes | incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times |
| What is Rogam | rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D |
| Discovery of first Rh antigen | Levine and Stetson. |
| Rh is named after | Rhesus monkeys |
| Genes for ABO antigens are located on | Chromosome #9 |
| Genes for D antigen are located on | Chromosome #1 |
| What is a Rh Control? | identical to anti-D sera but not antibody. |
| Weak D testing includes | incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times |
| What is Rogam | rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D |
| What is 25% albumin used for | reduces zeta potential. allowing rbc to approach each other |
| What does PEG do (polyethylene Glycol) | removes water from test. Most sensitive and most false positives results. |
| Agglutination or Hemolysis at any stage of antibody screen | is a positive result. |
| Most common cold antibodies | anti- N, anti-P and anti I IgM immediate spin |
| Most common warm antibodies | Rh,Kell, Kidd, Duffy |
| What does it mean if you have a positive auto control? | suggest autoantibody or medication antibody. Usually Lea or Leb |
| What are the dosage antibodies | kidd,dffy,Rh,MNs Kidds and Duffy the monkey eat M&N |
| Lewis system | antigen made in tissue and secreted into blood. Inheritance depends on both genes and secretor genes. |
| Only in childhood can show this lewis pattern | Le(a+b-) or Le (a+b+) |
| What is the related disease state with Lewis antigens | peptic ulcers and H.Pylori Tumor formation, transplant failures |
| I Blood system (individuality), at birth is? In adults? | rich in i as infant rich in I as adult |
| Production of Autoanti-I are associated with what disease states? | Mycopasma pnumoniae and monucleosis |
| M and N antiges are found on | glycoprotein A |
| S and S antiges are found on | glycoprotein B |
| Anti- M is associated with | Burn patients of bacterial infections |
| Cold antibodies (naturally occuring ) are | LiPMAN |
| K | Kell |
| k | cellano |
| KPa | penny |
| KPb | ratenberg |
| Kell is associate with which syndrome | McLeod -muscle and nerve, slow from of muscular distrophy. acanthrocyte prodction. |
| Fy(a-b-) null phenotype- common in blacks in africa can resist | plasmodium |
| Kidd antibodies are common in | HTR |
| Diego is higher in | Asians and South American populations |
| Diego is useful in | mongolian ancestry research |
Created by:
Kateskate
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