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Blood Bank

Rh Blood Group System,Screening, Blood Group Systems

QuestionAnswer
Discovery of first Rh antigen Levine and Stetson.
Rh is named after Rhesus monkeys
Genes for ABO antigens are located on Chromosome #9
Genes for D antigen are located on Chromosome #1
What is a Rh Control? identical to anti-D sera but not antibody.
Weak D testing includes incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times
What is Rogam rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D
Discovery of first Rh antigen Levine and Stetson.
Rh is named after Rhesus monkeys
Genes for ABO antigens are located on Chromosome #9
Genes for D antigen are located on Chromosome #1
What is a Rh Control? identical to anti-D sera but not antibody.
Weak D testing includes incubating 37 degrees C for 15 to 60 minutes. Cells are washed 3-4 times
What is Rogam rh immune globulin to prevent rh neg individuals who are exposed to rh positive RBC from developing Anti-D
What is 25% albumin used for reduces zeta potential. allowing rbc to approach each other
What does PEG do (polyethylene Glycol) removes water from test. Most sensitive and most false positives results.
Agglutination or Hemolysis at any stage of antibody screen is a positive result.
Most common cold antibodies anti- N, anti-P and anti I IgM immediate spin
Most common warm antibodies Rh,Kell, Kidd, Duffy
What does it mean if you have a positive auto control? suggest autoantibody or medication antibody. Usually Lea or Leb
What are the dosage antibodies kidd,dffy,Rh,MNs Kidds and Duffy the monkey eat M&N
Lewis system antigen made in tissue and secreted into blood. Inheritance depends on both genes and secretor genes.
Only in childhood can show this lewis pattern Le(a+b-) or Le (a+b+)
What is the related disease state with Lewis antigens peptic ulcers and H.Pylori Tumor formation, transplant failures
I Blood system (individuality), at birth is? In adults? rich in i as infant rich in I as adult
Production of Autoanti-I are associated with what disease states? Mycopasma pnumoniae and monucleosis
M and N antiges are found on glycoprotein A
S and S antiges are found on glycoprotein B
Anti- M is associated with Burn patients of bacterial infections
Cold antibodies (naturally occuring ) are LiPMAN
K Kell
k cellano
KPa penny
KPb ratenberg
Kell is associate with which syndrome McLeod -muscle and nerve, slow from of muscular distrophy. acanthrocyte prodction.
Fy(a-b-) null phenotype- common in blacks in africa can resist plasmodium
Kidd antibodies are common in HTR
Diego is higher in Asians and South American populations
Diego is useful in mongolian ancestry research
Created by: Kateskate