WVSOM Class of 2012 Cytoskeleton
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show | microfilaments, intermediate fibers, microtubules
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show | intermediate filament
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energy for microfilament polymerization comes from? what about microtubules? | show 🗑
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show | actin and myosin; tubulin; keratins and nuclear lamins
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function of cytoskeletal bundles? networks? anchoring? | show 🗑
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show | hydrolyze ATP to crawl along filaments
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show | increase or decrease filament length to induce pushing or pulling force
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the most abundant intracellular protein is what? | show 🗑
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show | f-actin filaments; ATP hydrolysis
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rope-like alpha helices that wrap around f-actin? | show 🗑
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regulatory subunits binding tropomyosin and actin? | show 🗑
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actin crosslinking protein that forms networks in RBC's? | show 🗑
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show | dystrophin
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show | myosins
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show | stress fibers
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energy for assembly of microtubules come from what? | show 🗑
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show | positive end
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alpha and beta tubulins bind each other to form what? | show 🗑
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show | tubulins (alpha and beta)
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show | 13
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rows of tubulins are called what? | show 🗑
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show | chemotherapy
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crosslinking proteins in microtubules are called what? | show 🗑
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show | Dynein and Kinesin
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what is the function of dynein? | show 🗑
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show | moves cytosolic vesicles and bipartites associating with the mitotic spindle
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examples of Microtubular Mediated Motility? | show 🗑
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what is the arrangement of microtubules within flagella and cilia? | show 🗑
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show | dynein arms
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show | anterograde transport
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from synapse to cell body is called? | show 🗑
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show | basal body
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show | believed to serve as nucleation centers for flagella and cilia outgrowth, they coordinate beating of cilia
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show | polar, kinetochore, and astral
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show | positive, negative
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spindle shaped complexes of microtubules, which serve to separate daughter chromosomes during mitosis: | show 🗑
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An area at each end of the spindle where the microtubules converge? | show 🗑
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A protein structure joining centromeres to the microtubules of the spindle? | show 🗑
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during anaphase, what happens to the microtubules? | show 🗑
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a small organelle consisting of a perpendicular pair of centrioles surrounded by a matrix of two proteins: | show 🗑
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the core of a centrosome, consisting of 9 microtubular triplets, but not including the surrounding protein matrix: | show 🗑
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All intermediate filaments consist of alpha helical cores with similar sequences. These are what? | show 🗑
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show | keratins
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show | desmin
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two major distinctions between the assembly of intermediate filaments and that of microfilaments or microtubules? | show 🗑
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intermediate filament crosslinking occurs using what structures? | show 🗑
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show | an IFAP that anchors desmin to the plasma membrane, as well as spectrin to the band 3 anion transporter of erythrocytes
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On the nucleoplasmic face of the nuclear envelope there is a meshwork of intermediate filaments known as the: | show 🗑
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the intermediate filaments are entirely what function? | show 🗑
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show | keratins, nuclear lamins, and desmins
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these are used to identify the origin of tumor cells, which often lose other distinguishing characteristics: | show 🗑
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3 parts of nuclear lamina? | show 🗑
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which lamin remains bound to the vesicles? | show 🗑
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generally speaking what are the functions of all 3 components of the cytoskeleton? | show 🗑
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show | cross-linking proteins
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show | carry a cargo along the filament (e.g. a vesicle) or they cause two filaments to slide past each other (e.g. muscle contraction)
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Finger like projections of the plasma membrane, supported by internal actin bundles: | show 🗑
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show | increase the surface area of the plasma membrane for absorption
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what is the most common myosin isoform? | show 🗑
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myosin subunits are what structure? | show 🗑
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myosin subunits consist of what two factors? | show 🗑
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show | tails and globular heads
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two tails of myosin coil around each other to form dimers; this process uses what for energy? | show 🗑
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in the sliding filament model, contractions cause what to slide along what? | show 🗑
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Movement of vesicles through the intracellular membrane system is often directed along what two things? | show 🗑
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show | actomyosin
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ameboid movement is made possible by what structures? | show 🗑
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how are microtubules arranged with regard to polarity? | show 🗑
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show | axons
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show | microtubule organizing centers (MTOC)
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show | mitotic apparatus
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show | during the S phase
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show | astral MT
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which MT extend halfway across the spindle? | show 🗑
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show | kinetochore MT
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