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WVSOM Class of 2012 Cytoskeleton

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show microfilaments, intermediate fibers, microtubules  
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show intermediate filament  
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energy for microfilament polymerization comes from? what about microtubules?   show
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show actin and myosin; tubulin; keratins and nuclear lamins  
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function of cytoskeletal bundles? networks? anchoring?   show
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show hydrolyze ATP to crawl along filaments  
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show increase or decrease filament length to induce pushing or pulling force  
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the most abundant intracellular protein is what?   show
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show f-actin filaments; ATP hydrolysis  
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rope-like alpha helices that wrap around f-actin?   show
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regulatory subunits binding tropomyosin and actin?   show
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actin crosslinking protein that forms networks in RBC's?   show
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show dystrophin  
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show myosins  
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show stress fibers  
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energy for assembly of microtubules come from what?   show
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show positive end  
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alpha and beta tubulins bind each other to form what?   show
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show tubulins (alpha and beta)  
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show 13  
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rows of tubulins are called what?   show
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show chemotherapy  
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crosslinking proteins in microtubules are called what?   show
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show Dynein and Kinesin  
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what is the function of dynein?   show
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show moves cytosolic vesicles and bipartites associating with the mitotic spindle  
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examples of Microtubular Mediated Motility?   show
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what is the arrangement of microtubules within flagella and cilia?   show
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show dynein arms  
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show anterograde transport  
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from synapse to cell body is called?   show
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show basal body  
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show believed to serve as nucleation centers for flagella and cilia outgrowth, they coordinate beating of cilia  
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show polar, kinetochore, and astral  
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show positive, negative  
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spindle shaped complexes of microtubules, which serve to separate daughter chromosomes during mitosis:   show
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An area at each end of the spindle where the microtubules converge?   show
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A protein structure joining centromeres to the microtubules of the spindle?   show
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during anaphase, what happens to the microtubules?   show
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a small organelle consisting of a perpendicular pair of centrioles surrounded by a matrix of two proteins:   show
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the core of a centrosome, consisting of 9 microtubular triplets, but not including the surrounding protein matrix:   show
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All intermediate filaments consist of alpha helical cores with similar sequences. These are what?   show
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show keratins  
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show desmin  
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two major distinctions between the assembly of intermediate filaments and that of microfilaments or microtubules?   show
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intermediate filament crosslinking occurs using what structures?   show
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show an IFAP that anchors desmin to the plasma membrane, as well as spectrin to the band 3 anion transporter of erythrocytes  
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On the nucleoplasmic face of the nuclear envelope there is a meshwork of intermediate filaments known as the:   show
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the intermediate filaments are entirely what function?   show
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show keratins, nuclear lamins, and desmins  
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these are used to identify the origin of tumor cells, which often lose other distinguishing characteristics:   show
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3 parts of nuclear lamina?   show
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which lamin remains bound to the vesicles?   show
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generally speaking what are the functions of all 3 components of the cytoskeleton?   show
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show cross-linking proteins  
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show carry a cargo along the filament (e.g. a vesicle) or they cause two filaments to slide past each other (e.g. muscle contraction)  
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Finger like projections of the plasma membrane, supported by internal actin bundles:   show
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show increase the surface area of the plasma membrane for absorption  
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what is the most common myosin isoform?   show
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myosin subunits are what structure?   show
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myosin subunits consist of what two factors?   show
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show tails and globular heads  
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two tails of myosin coil around each other to form dimers; this process uses what for energy?   show
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in the sliding filament model, contractions cause what to slide along what?   show
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Movement of vesicles through the intracellular membrane system is often directed along what two things?   show
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show actomyosin  
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ameboid movement is made possible by what structures?   show
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how are microtubules arranged with regard to polarity?   show
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show axons  
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show microtubule organizing centers (MTOC)  
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show mitotic apparatus  
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show during the S phase  
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show astral MT  
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which MT extend halfway across the spindle?   show
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show kinetochore MT  
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