Clls-302 final exam
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Glassware calibrated to deliver the amount of liquid that is marked on the instrument is labeled what | TD
🗑
|
||||
| A substance that is dissolved in a liquid is a | solute
🗑
|
||||
| A substance that dissolves a substance is a | solvent
🗑
|
||||
| The combination of a solute and a solvent is a | solution
🗑
|
||||
| Glassware is calibrated at | 20 degrees C
🗑
|
||||
| Chemical bond in which 2 or more atoms share their valence electrons is a | covalent bond
🗑
|
||||
| A chemical bond in which 1 or more valence electrons is completely transferred from 1 atom to another | Ionic
🗑
|
||||
| What is the term for a solution that contains relatively little solute | dilute
🗑
|
||||
| What is the term for a solution that contains a large amount of dissolved solute | concentrated
🗑
|
||||
| Beer's Law | (A unknown/A standard) X C standard
🗑
|
||||
| The purpose of a light filter in the spectrophotometer is | Isolate individual wavelengths of light
🗑
|
||||
| Icteric | excessive amount of bilirubin
🗑
|
||||
| Lipemic | excessive amount of fats
🗑
|
||||
| Hemolyzed | excessive amount of blood
🗑
|
||||
| Carbohydrates are characterized by what properties | # of sugar units, location of the CO functional group, and size of the base carbon chain
🗑
|
||||
| Carbohydrate with chainc of 2-10 sugars units is what | oligosaccharides
🗑
|
||||
| Insulin and glucagon are produced by which cells | cells of the islets of Langerhans
🗑
|
||||
| Hormone that facilitates the entry of glucose into the cell is | insulin
🗑
|
||||
| In hypoglycemia, the body responds to low glucose levels by releasing | glucagon and epinephrine
🗑
|
||||
| Ketoacidosis | an acute complication of diabetes mellitus
🗑
|
||||
| Autoimmune disorders are associated with what type of diabetes | type 1
🗑
|
||||
| What is the product measures in the hexokinase method for measuring glucose | amount of NADPH produced from the reduction of NADP
🗑
|
||||
| Genetic defect in carbohydrate metabolism in which there are deficiencies of specific enzymes that cause an alteration in glycogen metabolism | Galactosemia
🗑
|
||||
| Glucose is stored in muscle and the liver as | glycogen
🗑
|
||||
| HbA 1C | The fraction of adult hemoglobin that is often measured to assess glycemic control for the past 3 months
🗑
|
||||
| What method is the most specific for testing glucose? It only reacts with Beta-D-Glucose | Glucose oxidase
🗑
|
||||
| Primary function of albumin in the circulation is to | regulate the oncotic pressure
🗑
|
||||
| Guthrie bacterial inhibition test is used to detect elevated levels of | Phenyalanine
🗑
|
||||
| The elemental component that sets proteins apart from lipid and carbohydrates is | nitrogen
🗑
|
||||
| Homocysteinemia is associated with | a nutritional deficiency of folate and vitamin B6
🗑
|
||||
| Alpha fetoprotein may be included in a testing panel for | prenatal screening for neural tube defects
🗑
|
||||
| A protein that is formed in response to a specific stimulus and is synthesized by plasma cells is known as | Immunoglobulin
🗑
|
||||
| Most common method testing for albumin determination | Dye Binding method
🗑
|
||||
| What are the common dyes us in Dye binding | BCG, BCP, and Methyl Orange
🗑
|
||||
| A/G ratio is | the calculation commonly used to assess the ratio of the major plasma protein components
🗑
|
||||
| haptoglobin | the protein that is able to bind free hemoglobin in the plasma
🗑
|
||||
| Monoclonal band of IgM in gamma globulin region, serum hyperviscosity, less bone pain & fewer infections that multiple myeloma | Waldenstrom's macroglobulinemia
🗑
|
||||
| higher incidence of infections, monoclonal band of IgG or IgA in the gamma globulin region, severe bone pain | Multiple myeloma
🗑
|
||||
| What protein is activated by thrombin to form a clot | fibrinogen
🗑
|
||||
| Classic method for quantification of total proteins is based on what | Kjeldahl method
🗑
|
||||
| Protein synthesis occurs mainly in what organ | liver
🗑
|
||||
| C-reactive protein has become an effective tool in predicting what | cardiovascular inflammation
🗑
|
||||
| Zero-order kinetics | clinical assays that measure enzyme activities
🗑
|
||||
| What enzyme shows the greatest specificity for hepatocellular liver damage | alanine aminotransferase
🗑
|
||||
| A woman in her 3rd trimester of pregnancy would be expected to have high levels of what | ALP
🗑
|
||||
| Coenzyme | an organic, non-protein molecule that is necessary for enzyme activation
🗑
|
||||
| Extremely elevated activity of what enzyme is consistent with Duchenne type MD | CK
🗑
|
||||
| What enzyme is used in the diagnosis of prostatic carcinoma | ACP
🗑
|
||||
| Primary tissue source of amylase | pancreas
🗑
|
||||
| Enzyme to assess liver function | Alanine aminotransferase, alkaline phosphatase, and gamma-glutamyltransferase
🗑
|
||||
| Factors determining the rate of enzyme reaction: | pH, temperature, cofactors, substrate concentration
🗑
|
||||
| what enzymes are generally used quantitatively to help diagnose acute pancreatitis | Amylase and lipase
🗑
|
||||
| What is the diagnosis: CK-moderately increased, LD-moderately increased, and LD-1 is increased | Myocardial infarcction
🗑
|
||||
| fatty acids yield energy through | beta oxidation
🗑
|
||||
| The formula used to calculate indirect LDL cholesterol levels is: | Friedewald equation
🗑
|
||||
| What lipid fractions are very large molecules with a low density & give plasma a milky appearance when present in increased amounts? | chylomicrons
🗑
|
||||
| What forms of cholesterol will be measured using the cholesterol oxidase enzymatic method? | esterfied and free
🗑
|
||||
| Which alipoprotein is a variant of LDL and has been associated with elevated risk of CHD | Lp(a)
🗑
|
||||
| What tests would be included in a routine lipid profile? | Cholesterol, LDL-cholesterol, HDL cholesterol, triglycerides
🗑
|
||||
| Liebermann-Burchardt procedure | the reference method for cholesterol analysis that involves an extraction process used to measure free and cholesterol easters
🗑
|
||||
| Measurement of HDL cholesterol using a direct method that suppresses the enzymatic cholesterol other than HDL is called | hologenous assay
🗑
|
||||
| The most important use of Phospholipid measurement is to assess | fetal lung maturity
🗑
|
||||
| The lipoprotein that has the highest ration of lipid to protein is | HDL
🗑
|
||||
| Increased blood ammonia levels may be associated with | hepatic failure, encephalopathy, and neurological changes
🗑
|
||||
| What is the major organ for excretion and reabsorption of metabolized materials | kidney
🗑
|
||||
| Use of a cation exchange resin, and elution step and quantification by Berthelot reaction describes the method to quantify | uric acid
🗑
|
||||
| In a diacetyl monoxime method, diacetyl reacts directly with urea | urea
🗑
|
||||
| The Jaffe reaction is used for the quantification of | creatinine
🗑
|
||||
| Caraway method | uric acid
🗑
|
||||
| Azotemia is the elevation of what | uric acid, creatinine, and urea
🗑
|
||||
| The normal ratio for creatinine | 10:1 to 20:1
🗑
|
||||
| What is the most common test used to assess kidney function | urinalysis
🗑
|
||||
| Hematuria, proteinuria, elevated BUN & Creatinine, and Hyaline & Granular Casts | Acute Glomerularnephritis
🗑
|
||||
| Endogenous substance used to assess the glomerular filtration rate that affords the most accurate measure of renal clearance | creatinine
🗑
|
||||
| The nitrogenous end product of catabolism of purines from dietary endogenous sources is | uric acid
🗑
|
||||
| Creatinine reacts with strong alkaline picrate to form a yellow-red compound. This reaction is | Jaffe reaction
🗑
|
||||
| Uric acid may be determined with | The enzyme urease and the formation of a blue color with phosphotungstic acid
🗑
|
||||
| urea ref range | 6-20mg/dL
🗑
|
||||
| Creatinine ref range | 0.6-1.1 mg/dL
🗑
|
||||
| Uric acid ref range | 0.5-7.2 mg/dL
🗑
|
||||
| Ammonia ref range | 10-60 microliters/dl
🗑
|
||||
| The cation present in the greatest concentration extracellularly is | sodium
🗑
|
||||
| Sodium and potassium levels in the blood are measured using | ion selective electrodes
🗑
|
||||
| Lab method of choice for detecting cystic fibrosis | sweat test
🗑
|
||||
| Electrolyte that is the end product of anaerobic glycolysis and is an early indicator of the severity of O2 depletion | lactate
🗑
|
||||
| Electrolytic anion that is reabsorbed with Na+ in the proximal tubule | chloride
🗑
|
||||
| Formula for Anion Gap | (Na+ + K+) - (Cl- + HCO3-)
🗑
|
||||
| Which organs play an important role in the maintaining the blood pH level? | lung and kidney
🗑
|
||||
| Metabolic acidosis is | a disorder caused by kidney dysfunction
🗑
|
||||
| Respiratory acidosis is | disorder caused by lung dysfunction
🗑
|
||||
| Metabolic acidosis | decreased pH, decreased Bicarb
🗑
|
||||
| Metabolic Alkalosis | increased pH, increased Bicarb
🗑
|
||||
| Respiratory Acidosis | decreased pH, increased pCO2
🗑
|
||||
| Respiratory Alkalosis | increased pH, decrease pCO2
🗑
|
||||
| The iron-transport protein in the blood is | tranferrin
🗑
|
||||
| Disorder associated with abnormal excessive absorption of iron from normal diet | hemochromotosis
🗑
|
||||
| TIBC measures the serum iron-transporting capacity for | transferrin
🗑
|
||||
| The PTH assay that measures both the n and the c-terminal end of molecule | intact PTH assay
🗑
|
||||
| The chromogen that produce a colored complex with iron is most commonly used in laboratory analysis of total iron levels | hemochromatosis
🗑
|
||||
| What trace element is a metal cofactor in the reactions of over 300 enzymes within the body | zinc
🗑
|
||||
| which electrolyte is a cofactor in the reactions of over 300 enzymes in the body | magnesium
🗑
|
||||
| Physiologically active form of calcium is | ionized
🗑
|
||||
| The formation of a molybdenum blue complex is associated with the quantification of | phosphate
🗑
|
||||
| What reagent is used in a colorimetric method to quantify the concentration of serum calcium | Cresolphthalein complexone
🗑
|
||||
| What is the primary storage form of iron | ferritin
🗑
|
||||
| A person who is deficient of chromium may develop | insulin resistance and glucose intolerance
🗑
|
||||
| cobalt is an essential element in which of the following vitamins | vitamin B12
🗑
|
||||
| Serum iron: decreased, TIBC: increased, Transferrin: decreased, Serum ferritin: decreased | Iron deficiency anemia
🗑
|
||||
| Enzymes most commonly analyzed to assess liver condition are | ALT and AST
🗑
|
||||
| What disease is the measurement of brain type natriuretic peptide most useful | congestive heart failure
🗑
|
||||
| The enzyme system that catalyzes the conjugation of bilirubin is known as | Uridine diphosphate glucotonyl transferase
🗑
|
||||
| The most common method of bilirubin testing is | Jendrassik and Groff method
🗑
|
||||
| The enzyme that originates in the liver, correlates with elevated ALP liver isoenzymes and is very sensitive to metastatic liver cancer | 5'nucleotidase
🗑
|
||||
| Chronic hepatitis is diagnosed by the presence of what clinical finding | elevated levels of liver enzymes for greater than 6 month period of time
🗑
|
||||
| What is the clinical usefulness of measuring Albumin cobalt binding for IMA | Is used to diagnose and monitor Acute MI
🗑
|
||||
| The most common method of Urobilinogen testing | Malloy and Evelyn
🗑
|
||||
| Addison's disease corresponds with | decreased cortisol levels
🗑
|
||||
| Pituitary secretion of ACTH is inhibited by elevated levels of | cortisol
🗑
|
||||
| Glucocorticoid hormones major function is the regulation of | blood glucose hemostasis
🗑
|
||||
| A prolactinoma is a _______ that secretes prolactin | pituitary tumor
🗑
|
||||
| The principle method used to measure hormone levels in blood in most clinical labs | Immunoassays
🗑
|
||||
| Estrogen is what type of hormone | steroid
🗑
|
||||
| Follicle Stimulating Hormone is what type of hormone | glycoprotein
🗑
|
||||
| progesterone is what type of hormone | steroid
🗑
|
||||
| lutenizing hormone is what type of hormone | glycoprotein
🗑
|
||||
| androsterone is what type of hormone | steroid
🗑
|
||||
| Oncogene | a gene which encodes a protein that, when mutated, promotes uncontrolled cell growth
🗑
|
||||
| Glycolytic enzymes are effective indicators of tumor progression because | malignant cells have high rate of glycolytic activity
🗑
|
||||
| The most ommon method of tumor marker analysis is | quantitative immunoassay
🗑
|
||||
| NMP is a tumor marker designed for what purpose | test for recurrence of bladder cancer
🗑
|
||||
| A markedly elevated clinical usefulness of measuring carcinoembyonic antigen | monitoring for recurrence of colon cancer
🗑
|
||||
| What is used to assist in diagnosing pancreatic cancer | Serum amylase, CA 50 and CA 19.9
🗑
|
||||
| Why is the administration of Leucovorin necessary after a methotrexate infusion | to reverse the effects of DNA synthesis inhibition
🗑
|
||||
| Mechanistic | Cellular and biological effects of toxins
🗑
|
||||
| clinical | Interrelationship of toxins and disease
🗑
|
||||
| Descriptive | analysis of animal exposure to toxins
🗑
|
||||
| forensic | mediolegal consequences of toxin exposure
🗑
|
||||
| A(unk)/A(std) X C(std) = C(unk) | Beer's law
🗑
|
||||
| LDL=TC-HDL-(trig/5) | Friedwalds formula
🗑
|
||||
|
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
pamela18
Popular Laboratory Science sets