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toxicology and therapeutic drug monitoring

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Question
Answer
Cannabinoids are found in   Marijuana  
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When the rate of drug metabolism equals the rate of metabolism and excretion is known as   Steady state  
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Peak levels of a therapeutic drug should be drawn _____ a dose   1 hour  
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Gentamicin and tobramycin are included in which class of therapeutic drugs?   Antibiotics  
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Which therapeutic drug is associated with Red Man's Syndrome?   Vancomycin  
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What is referred to as the date rape drug?   GHB  
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Cyclosporine and tacrolimus are two therapeutic drugs commonly measured following an   Organ transplant  
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Reyes syndrome in children and adolescents is a toxic effect of what drug?   Salicylate  
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Theophylline belongs to which class of drugs?   Bronchodilators  
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What drug is used to treat Bipolar disorder?   Lithium  
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Which group of drugs are used to treat cold and allergy reactions?   amphetamines  
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Which alcohol is converted to formaldehyde by the liver and can lead to death?   Methanol  
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The first pass effect of drug metabolism occurs in which major organ in the body?   Liver  
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What are some of the specimen requirements for alcohol toxicology testing?   Performed on plasma, serum, and whole blood Do not use alcohol prep pad Keep specimen capped  
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What antipychotic drugs takes 2-4wks for the therapeutic effect to occur?   Doxepin and Imipramine  
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What is the therapeutic drug monitoring?   The dose gives maximal therapeutic effect and the minimal toxic effect.  
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Most drugs are bound to what in the body?   Proteins  
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Digoxin belongs to what class of drugs?   Cardioactive  
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Chronic toxicity   is due to repeated frequent doses over time  
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Methods of alcohol testing   Enzymatic, gas chromatography, and Osmolarity  
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Anti hypertensive drugs like sodium nitroprusside's primary role in treating high blood pressure.   dilate arteries and veins  
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Group 1 analytes   Acetaminophen, Salicylate, Ethanol, and Carbon monoxide  
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This synthetic substance is associated with toxic hepatitis, stroke, and MI   Anabolic steroids  
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Aminoglycerides are used to   treat gram negative bacteria  
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The distribution of an administered drug into interstitial and intracellular fluid depends on which physiological factors?   Blood flow, capillary permeability, binding of drugs to proteins, and tissue volume.  
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Amphetamines are described as   Psychomotor stimulants that act by releasing monoamines from nerve terminals in the brain  
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Drugs that bind to physiological receptors & mimic the regulatory effect of endogenous signaling compounds   agonists  
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Elimination half life is   the time it takes for the amount of drug in the blood to reduce by 50%  
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What type of drug is Tacrolimua?   Immunosuppressant  
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What is the major organ involved in drug absorption   liver  
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Created by: pamela18
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