toxicology and therapeutic drug monitoring
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Cannabinoids are found in | Marijuana
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When the rate of drug metabolism equals the rate of metabolism and excretion is known as | Steady state
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Peak levels of a therapeutic drug should be drawn _____ a dose | 1 hour
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Gentamicin and tobramycin are included in which class of therapeutic drugs? | Antibiotics
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Which therapeutic drug is associated with Red Man's Syndrome? | Vancomycin
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What is referred to as the date rape drug? | GHB
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Cyclosporine and tacrolimus are two therapeutic drugs commonly measured following an | Organ transplant
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Reyes syndrome in children and adolescents is a toxic effect of what drug? | Salicylate
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Theophylline belongs to which class of drugs? | Bronchodilators
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What drug is used to treat Bipolar disorder? | Lithium
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Which group of drugs are used to treat cold and allergy reactions? | amphetamines
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Which alcohol is converted to formaldehyde by the liver and can lead to death? | Methanol
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The first pass effect of drug metabolism occurs in which major organ in the body? | Liver
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What are some of the specimen requirements for alcohol toxicology testing? | Performed on plasma, serum, and whole blood
Do not use alcohol prep pad
Keep specimen capped
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What antipychotic drugs takes 2-4wks for the therapeutic effect to occur? | Doxepin and Imipramine
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What is the therapeutic drug monitoring? | The dose gives maximal therapeutic effect and the minimal toxic effect.
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Most drugs are bound to what in the body? | Proteins
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Digoxin belongs to what class of drugs? | Cardioactive
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Chronic toxicity | is due to repeated frequent doses over time
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Methods of alcohol testing | Enzymatic, gas chromatography, and Osmolarity
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Anti hypertensive drugs like sodium nitroprusside's primary role in treating high blood pressure. | dilate arteries and veins
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Group 1 analytes | Acetaminophen, Salicylate, Ethanol, and Carbon monoxide
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This synthetic substance is associated with toxic hepatitis, stroke, and MI | Anabolic steroids
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Aminoglycerides are used to | treat gram negative bacteria
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The distribution of an administered drug into interstitial and intracellular fluid depends on which physiological factors? | Blood flow, capillary permeability, binding of drugs to proteins, and tissue volume.
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Amphetamines are described as | Psychomotor stimulants that act by releasing monoamines from nerve terminals in the brain
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Drugs that bind to physiological receptors & mimic the regulatory effect of endogenous signaling compounds | agonists
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Elimination half life is | the time it takes for the amount of drug in the blood to reduce by 50%
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What type of drug is Tacrolimua? | Immunosuppressant
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What is the major organ involved in drug absorption | liver
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