Capillaries & Lymph
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What is a precapillary sphincter? | show 🗑
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show | Intermittent contraction of the precapillary sphincters
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What is the flow rate generally dependent upon? | show 🗑
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TRUE or FALSE: "True" capillaries have no smooth muscle | show 🗑
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Describe the structure of a capillary | show 🗑
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show | FALSE: ECs are separated by intercellular cleft, thru which fluid & small dissolved molecules can flow
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What is the fxn of the plasmalemma in regards to material transport? | show 🗑
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show | Rare combinations of vesicles
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What sorts of nutrients can diffuse directly thru a cell membrane? | show 🗑
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How do water soluble materials diffuse? | show 🗑
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show | Brain: pores are almost sealed by tight jxns; Liver: pores are much larger
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show | Fluid in the spaces b/n the cells
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Describe interstitial fluid | show 🗑
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What happens when there is a lot of intercellular water flow? | show 🗑
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What determines the osmotic pressures of a capillary? | show 🗑
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show | NFP = Capillary pressure - Interstitial fluid pressure - Plasma colloid pressure + interstitial fluid colloid osmotic pressure
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Which forces are responsible for the pressure pushing/pulling out of the capillary? Pushing/pulling into the capillary? | show 🗑
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show | By an isogravimetric method - ~17mmHg
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show | ~25mmHg; when the precapillary sphincter is closed, pressure equals that of a venule (~10mmHg), so the pressure averages ~17mmHg
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What is the value of interstitial fluid hydrostatic pressure in loose subQ tissue? | show 🗑
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show | ~ -5mmHg
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What is the value of interstitial fluid hydrostatic pressure in the epidural space? | show 🗑
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What is the value of interstitial fluid hydrostatic pressure in the intrapleural space? | show 🗑
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show | Removal of fluid from the interstitial space by the lymph system.
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Describe Plasma Colloid Osmotic Pressure | show 🗑
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show | Normal = 28mmHg; 19mmHg due to dissolved protein, 9mmHg due to Na & K "held" by that protein (called the Donnan effect)
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show | Some protein does leak from the plasma; Net interstitial fluid (Pi-if) = 8mmHg
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What is the net filtration force at the ARTERIAL end of the capillary? Does this value indicate net fluid into or out of the capillary? | show 🗑
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What is the net filtration force at the VENOUS end of the capillary? Does this value indicate net fluid into or out of the capillary? | show 🗑
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show | Hydrostatic force (BP)
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show | Osmotic pressure
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Why does it not patter that filtration pressure (13mmHg) is greater than reabsorption pressure (7mmHg)? | show 🗑
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What are the 5 functions of the lymphatic system? | show 🗑
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What drains into the left thoracic lymph duct? | show 🗑
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Where does the left thoracic duct join? | show 🗑
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show | Lymphatics from the right arm, shoulder,and upper chest
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Where does the right thoracic duct join? | show 🗑
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Discuss the valves of the lymphatic capillaries | show 🗑
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What happens when the pressure equilibrates and the lymphatic capillary is compressed? | show 🗑
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show | Lymphatic capillary
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What are the cellular extensions into the main lymphatic channel called? | show 🗑
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show | The valves are pushed open
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What happens when the lymphatics are compressed? | show 🗑
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What are the forces driving lymph flow | show 🗑
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When smooth muscle cells on the walls of lymphatic capillaries contract, about how high can the pressure in the large thoracic duct reach? | show 🗑
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show |
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