Chapter 10 blood bank
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| What are two categories for required testing | immunohematologic
infectious disease screening
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| Why is donor blood tested | To ensure safety of blood and blood products
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| What is included in a immunohematologic test? | ABO/D - RBC antigens
antibody screen- clinically significant rbc antibodies
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| What infectious diseases are screen for? | Syphillis, Hepatitis B and C, Antibodies to Hepatitis B core, HIV 1 and 2, West Nile, and HTLV 1 and 2
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| What are the three methods used for viral marker testing? | Enzyme-linked immunosorbent assay (EIA): Uses enzyme conjugates and colored end product
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| Which serologic tests are used for syphillis? | RPR - Rapid plasma reagent used for screening
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| What type of blood products can transmit syphillis? | Spirochetes do not survive refrigerator temperatures, but fresh blood or platelets can transmit the disease
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| What are the three types of EIA |
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| Which is the most commonly used EIA | Solid Phase EIA
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| What are the four tests used to screen for donor blood for Hepatitis? | Hepatitis B surface antigen (HBsAg)
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| What is NAT? | Nucleic Acid Testing
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| When is HBsAg present | Found in large quantities during acute and chronic phase of the disease
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| Period of exposure and emergence of HBsAg is.... | 6 weeks
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| What test is used to confirm HIV and HTLV? | Western Blot
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| In a Western Blot, name two band that are detected if the person is HIV positive? | P24, GP41,GP120/160
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| HTLV-1 is associated with | adult T-cell leukemia
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| HTLV-II was first reported in patients with what type of leukemia? | patients with an atypical T-cell variant of hairy cell leukemia
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| What the screen test for West Nile? | NAT
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| Name an emerging South American disease that is now being screened? | Chagas Disease
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| A series of actions taken when a donor tests positive for a viral disease is known as? | Recipient Tracing (look-back)
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