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MED 3400 chapter 10
Chapter 10 blood bank
Question | Answer |
---|---|
What are two categories for required testing | immunohematologic infectious disease screening |
Why is donor blood tested | To ensure safety of blood and blood products |
What is included in a immunohematologic test? | ABO/D - RBC antigens antibody screen- clinically significant rbc antibodies |
What infectious diseases are screen for? | Syphillis, Hepatitis B and C, Antibodies to Hepatitis B core, HIV 1 and 2, West Nile, and HTLV 1 and 2 |
What are the three methods used for viral marker testing? | Enzyme-linked immunosorbent assay (EIA): Uses enzyme conjugates and colored end product |
Which serologic tests are used for syphillis? | RPR - Rapid plasma reagent used for screening |
What type of blood products can transmit syphillis? | Spirochetes do not survive refrigerator temperatures, but fresh blood or platelets can transmit the disease |
What are the three types of EIA | |
Which is the most commonly used EIA | Solid Phase EIA |
What are the four tests used to screen for donor blood for Hepatitis? | Hepatitis B surface antigen (HBsAg) |
What is NAT? | Nucleic Acid Testing |
When is HBsAg present | Found in large quantities during acute and chronic phase of the disease |
Period of exposure and emergence of HBsAg is.... | 6 weeks |
What test is used to confirm HIV and HTLV? | Western Blot |
In a Western Blot, name two band that are detected if the person is HIV positive? | P24, GP41,GP120/160 |
HTLV-1 is associated with | adult T-cell leukemia |
HTLV-II was first reported in patients with what type of leukemia? | patients with an atypical T-cell variant of hairy cell leukemia |
What the screen test for West Nile? | NAT |
Name an emerging South American disease that is now being screened? | Chagas Disease |
A series of actions taken when a donor tests positive for a viral disease is known as? | Recipient Tracing (look-back) |