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MED 3400 chapter 10

Chapter 10 blood bank

What are two categories for required testing immunohematologic infectious disease screening
Why is donor blood tested To ensure safety of blood and blood products
What is included in a immunohematologic test? ABO/D - RBC antigens antibody screen- clinically significant rbc antibodies
What infectious diseases are screen for? Syphillis, Hepatitis B and C, Antibodies to Hepatitis B core, HIV 1 and 2, West Nile, and HTLV 1 and 2
What are the three methods used for viral marker testing? Enzyme-linked immunosorbent assay (EIA): Uses enzyme conjugates and colored end product
Which serologic tests are used for syphillis? RPR - Rapid plasma reagent used for screening
What type of blood products can transmit syphillis? Spirochetes do not survive refrigerator temperatures, but fresh blood or platelets can transmit the disease
What are the three types of EIA
Which is the most commonly used EIA Solid Phase EIA
What are the four tests used to screen for donor blood for Hepatitis? Hepatitis B surface antigen (HBsAg)
What is NAT? Nucleic Acid Testing
When is HBsAg present Found in large quantities during acute and chronic phase of the disease
Period of exposure and emergence of HBsAg is.... 6 weeks
What test is used to confirm HIV and HTLV? Western Blot
In a Western Blot, name two band that are detected if the person is HIV positive? P24, GP41,GP120/160
HTLV-1 is associated with adult T-cell leukemia
HTLV-II was first reported in patients with what type of leukemia? patients with an atypical T-cell variant of hairy cell leukemia
What the screen test for West Nile? NAT
Name an emerging South American disease that is now being screened? Chagas Disease
A series of actions taken when a donor tests positive for a viral disease is known as? Recipient Tracing (look-back)
Created by: MLS2013