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Antibiotics-target Matching
Target and mechanism of action for: Chloramphenicol
Broad specturm Gr+ Gr- Rickettsias, Chlamydias and anaerobes Bacteriostatic effect, inhibit protein synthesis
Generic name of: Macrolides
1, Erythromycin 2, Azithromycin 3, Clarithriomycin
Target and mechanism of action for: Cephalosporins G1
Good Gr+ Modest Gr- Inhibit CW synthesis
Antibiotics, group II -Fungi. Side effects.
Allergy, may lead to: anafylactic shock, skin rash, serum sickness, fever, nephritis.
Streptomycin -side effect.
Could lead to permanent damage of the auditory nerve -> Hearing loss.
Target and mechanism of action for: Tetracyclines
Very broad spectrum Gr+ Gr- Rickettsias and Chlamydias Bacteriostatic effect
Tetracyclines -side effects.
1, Antibiosis -> Candidosis 2, Hepatic- and kidney damage 3, Brown discoloration of teeth (in children)
Target and mechanism of action for: Rifamycin and Riampin
Narrow spectrum Gr+ (even multiresistant) M.tuberculosis Bactericidal effect, inhibit synthesis of mRNA
Target and mechanism of action for: Penicillin -natural
Narrow spectrum Gr+ Gr- Spirochetes Inhibit CW synthesis
Generic name of: Tetracyclines
1, Oxytetracycline 2, Chlortetracycline 3, Tetracycline 4, Doxycycline 5, Minocycline
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