Question | Answer |
adenovirus | ds, replicates in nucleus, icosahedral, no envelope, respiratory, eye and GI disease |
Hepadnavirus | ds with short ss section. Icosahedral, envelope, diagnosed by serology- not culture |
Herpesvirus | ds, replicates in nucleus, icosahedral, envelope, demonstrates latency |
Herpes simplex virus | Type 1 (cold sores) and 2(genital). Skin an mucus membrane infections, encephalitis, easily grown in culture |
Varicella-zoster virus | chicken pox and shingles, Tzanck stain used for direct tissue exam to see giant cells |
Herpesvirus species | HSV, VZV, CMV, EBV, HHV 6,7,8 |
Cytomegalovirus | found in blood, urine, throat. Shell vial culture, serology. mono-like in adults, often fatal in immunocomprimised. |
Epstein-Barr virus | Heterophile positive in IM (85%), can produce tumors, not cultured. Serology detects early ag, viral capsid ag, nuclear ag. |
HHV 6,7,8 | 6+7 roseola, detect by molecular |
Papillomavirus | ds, no culture- molecular methods used, infect skin and mucus membrane, cause wart and cervical cancer |
parvovirus | ss, replicates in nucleus, small, no envelope, B-19, infects bone marrow cells. No culture- molecular |
poxvirus | ds, replicates in cytoplasm, largest virus, brick shaped with envelope, small pox, monkey pox |