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DNA viruses

Mod 5 lec 1

adenovirus ds, replicates in nucleus, icosahedral, no envelope, respiratory, eye and GI disease
Hepadnavirus ds with short ss section. Icosahedral, envelope, diagnosed by serology- not culture
Herpesvirus ds, replicates in nucleus, icosahedral, envelope, demonstrates latency
Herpes simplex virus Type 1 (cold sores) and 2(genital). Skin an mucus membrane infections, encephalitis, easily grown in culture
Varicella-zoster virus chicken pox and shingles, Tzanck stain used for direct tissue exam to see giant cells
Herpesvirus species HSV, VZV, CMV, EBV, HHV 6,7,8
Cytomegalovirus found in blood, urine, throat. Shell vial culture, serology. mono-like in adults, often fatal in immunocomprimised.
Epstein-Barr virus Heterophile positive in IM (85%), can produce tumors, not cultured. Serology detects early ag, viral capsid ag, nuclear ag.
HHV 6,7,8 6+7 roseola, detect by molecular
Papillomavirus ds, no culture- molecular methods used, infect skin and mucus membrane, cause wart and cervical cancer
parvovirus ss, replicates in nucleus, small, no envelope, B-19, infects bone marrow cells. No culture- molecular
poxvirus ds, replicates in cytoplasm, largest virus, brick shaped with envelope, small pox, monkey pox
Created by: kmaemom