Question | Answer |
Window period for HIV NAT | 9 days |
Window period for HIV EIA | 21 days |
Window period for HCV MP NAT | 7 days |
Window period for HCV EIA | 51 to 58 days |
Window period for Hep B Surface Ag | 30-38 days |
Window period for HBV NAT | 40 to 50 days MP NAT; ID NAT 15-34 days |
Window period for HTLV test | 80 |
Which transfusion transmitted agent is only tested for once in the lifetime of the donor? | T. cruzi, the agent for Chagas disease |
current estimate of risk of infection with HIV from blood transfusion | <1 in 2 million products |
What group and "clade" or subtype of HIV is most prevalent in the US? | Group M and clade B |
Window period for 3rd generation anti-HIV tests? | 22 days |
Window period for HIV NAT | 10 days |
False positive rate for anti-HIV EIA | 1 in 20K |
Reentry testing for an isolated reactive anti-HIV EIA donor can be performed after this time has elapsed | 8 weeks |
estimated risk of contracting hepatitis B from a transfusion in US | 1 in 250K |
required tests for hepatitis B for donated units of blood | anti-hepB core ab, HBV surface ag, HBV NAT |
window period for HBV NAT | 40 days |
Risk of transfusion transmitted HCV | 1 in 1.8 million units |
FDA regulations of HCV "lookbacks" require collection centers to notify consignees within how many days? | 30 days |
Deferral period for a donor who test positive for West Nile Virus by NAT | 120 days |
The first transfusion transmitted disease tested for in the USA | syphilis |
Why do most blood centers use treponemal tests for syphilis rather than non-treponemal tests (RPR)? | automation |
Current residual risk for HTLV infection from a blood transfusion | 1 in 2 million |
Diseases associated with HTLV1 infection | Adult T cell leukemia/lymphoma and tropical spastic paraperesis (HTLV1 associated myelopathy) |
Region where HTLV infection is endemic | Caribbean |
Proven disease associations with HTLV II | none |
T. cruzi is transmitted by this bug | triatomine bug |
Which transfusion transmitted disease test is only done once in a donor's lifetime? | T. cruzi antibody (Chaga's) |
Rate of septic transfusion reaction for apheresis platelets | 1 in 500K |
Source of contamination for majority of bacterially contaminated apheresis platelet units | skin (gram positive) |
Organisms most often implicated in septic transfusion reaction | gram negatives |
What malignancy has been reported in blood donors whose apheresis platelet units test culture positive for streptococcus bovis and streptococcus G? | colon cancer |
Verax test detects these | lipotechoic acid and lipopolysacchiride |